VIRS is an interactive web-based program designed for restriction endonuclease cut sites prediction and visualisation. The system permits to simultaneously process batch DNA sequences, and produces visual restriction maps with several useful options for users’ customisation. These options also perform in-depth analysis of the restriction maps, such as virtual electrophoretic result for digested fragments. Different from other analytical tools, VIRS not only displays visual outputs, but also provides the detailed properties of enzymes that are commercially avaialbe. All the information correlates with enzymes is stored in our database, which is updated monthly from the manufacturers’ websites.
Tree Gibbs Sampler is a software for identifying motifs by simultaneously using the motif overrepresentation property and the motif evolutionary conservation property. It identifies motifs without depending on pre-aligned orthologous sequences, which makes it useful for the extraction of regulatory elements in multiple genomes of both closely related and distant species.
Segment is a heuristic segmentation algorithm for DNA sequences. The program divides a DNA sequence into compositionally homogeneous domains by iterating a local optimization procedure at a given statistical significance.
Based on dataset containing both ORF and non-ORF recombination sites, iRSpot-Pse6NC is a predictor which using SVM classifier by incorporating the key hexamer features into the general PseKNC (Pseudo K-tuple Nucleotide Composition) via the binomial distribution feature selection approach.