LDhat 2.2a – Analysis of Recombination Rates from Population Genetic Data

LDhat 2.2a

:: DESCRIPTION

LDhat is a package written in the C and C++ languages for the analysis of recombination rates from population genetic data.

::DEVELOPER

McVean Group , the Auton lab

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Linux
  • C Compiler

:: DOWNLOAD

 LDhat

:: MORE INFORMATION

Citation

Auton and McVean,
Recombination rate estimation in the presence of hotspots.
Genome Research 17(8):1219-27, 2007.

FigTree 1.4.4 – Produce Figures of Phylogenetic Trees

FigTree 1.4.4

:: DESCRIPTION

FigTree is designed as a graphical viewer of phylogenetic trees and as a program for producing publication-ready figures. In particular it is designed to display summarized and annotated trees produced by BEAST.

::DEVELOPER

Andrew Rambaut Group

:: SCREENSHOTS

:: REQUIREMENTS

  • Windows / Linux / MacOS
  • Java

:: DOWNLOAD

FigTree

:: MORE INFORMATION

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PerlPrimer 1.1.21 – Open-source PCR Primer Design

PerlPrimer 1.1.21

:: DESCRIPTION

PerlPrimer is a free, open-source GUI application written in Perl that designs primers for standard PCR, bisulphite PCR, real-time PCR (QPCR) and sequencing. It aims to automate and simplify the process of primer design.

::DEVELOPER

Owen Marshall at Murdoch Childrens Research Institute

:: SCREENSHOTS

:: REQUIREMENTS

:: DOWNLOAD

PerlPrimer

:: MORE INFORMATION

Citation

Owen J. Marshall
PerlPrimer: cross-platform, graphical primer design for standard, bisulphite and real-time PCR
Bioinformatics (2004) 20 (15): 2471-2472.

ProteinModelerABC

ProteinModelerABC

:: DESCRIPTION

ProteinModelerABC is an evolutionary framework to estimate the best-fitting substitution model of protein evolution, among a set of complex substitution models that cannot be analyzed with traditional phylogenetic likelihood functions, with the approximate Bayesian computation (ABC) approach.

::DEVELOPER

David Ferreiro, Catarina Branco, Miguel Arenas

:: REQUIREMENTS

  •  Linux

:: DOWNLOAD

ProteinModelerABC

:: MORE INFORMATION

Citation

Ferreiro D, Branco C, Arenas M. 2024.
Selection among site-dependent structurally constrained substitution models of protein evolution by approximate Bayesian computation.
Bioinformatics, 40:3, btae096. https://doi.org/10.1093/bioinformatics/btae096

ProtASR 2.2 – Ancestral Sequence Reconstruction of Proteins accounting for Structural Constraints

ProtASR 2.2

:: DESCRIPTION

ProtASR is an evolutionary framework to reconstruct ancestral protein sequences accounting for structural constraints.

::DEVELOPER

Dr. Miguel Arenas

:: REQUIREMENTS

  • Linux

:: DOWNLOAD

ProtASR

:: MORE INFORMATION

Citation

Arenas M, Bastolla U.
ProtASR2: Ancestral reconstruction of protein sequences accounting for folding stability.
Methods Ecol Evol
. 2020; 11: 248–257. https://doi.org/10.1111/2041-210X.13341

POPGENE 1.32 – Population Genetic Analysis

POPGENE 1.32

:: DESCRIPTION

POPGENE is a user-friendly computer freeware for the analysis of genetic variation among and within populations using co-dominant and dominant markers. This package provides the Windows graphical user interface that makes population genetics analysis more accessible for the casual computer user and more convenient for the experienced computer user. Simple menus and dialog box selections enable you to perform complex analyses and produce scientifically sound statistics, thereby assisting you to adequately analyze population genetic structure using the target markers.

::DEVELOPER

POPGENE Team

:: SCREENSHOTS

:: REQUIREMENTS

  • Windows

:: DOWNLOAD

 POPGENE

:: MORE INFORMATION

GeneFinder 1.2.7 – Linkage Analysis with a Variety of Extensions

GeneFinder 1.2.7

:: DESCRIPTION

GeneFinder is a software package for linkage analysis with a variety of extensions.  GeneFinder continues a standard linkage software such as MERLIN by providing a more reasonable gene location estimation and the corresponding confidence interval estimate. In addition, GeneFinder provides a variety of linkage extensions such as adjusting for covariate heterogeneity, joint analysis of two linked disease susceptibility loci, linkage conditional on a known locus, etc.

::DEVELOPER

Wei-Min Chen

:: SCREENSHOTS

N/A

::REQUIREMENTS

  • Linux  / Windows / MacOsX

:: DOWNLOAD

 GeneFinder

:: MORE INFORMATION

ZincExplorer – Predictor of Protein Zinc-binding Sites

ZincExplorer

:: DESCRIPTION

ZincExplorer is a web server that could predict Zinc-binding sites from protein sequence.

::DEVELOPER

Ziding Zhang’s Lab

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Web Browser

:: DOWNLOAD

 NO

:: MORE INFORMATION

Citation:

Mol Biosyst. 2013 Sep;9(9):2213-22. doi: 10.1039/c3mb70100j.
ZincExplorer: an accurate hybrid method to improve the prediction of zinc-binding sites from protein sequences.
Chen Z, Wang Y, Zhai YF, Song J, Zhang Z.

piNet – Modular Network Models of Plant Immune Reponse

piNet

:: DESCRIPTION

piNet is a resource for interactively exploring modular network models of plant immune response.

::DEVELOPER

Ziding Zhang’s Lab

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Web Browser

:: DOWNLOAD

 NO

:: MORE INFORMATION

Citation:

Dong X., Jiang Z., Peng Y-L., Zhang Z. (2015)
Revealing Shared and Distinct Gene Network Organization in Arabidopsis Immune Responses by Integrative Analysis.
Plant Physiol. 2015 Mar;167(3):1186-203. doi: 10.1104/pp.114.254292.

WDRR – WD40 Repeat Recognition

WDRR

:: DESCRIPTION

WDRR is a new WD40 Repeat Recognition method, which uses predicted secondary structure information to generate candidate repeat segments, and further employs a profile-profile alignment to identify the correct WD40 repeats from candidate segments.

::DEVELOPER

Ziding Zhang’s Lab, China Agricultural University

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Web Server
  • PHP

:: DOWNLOAD

WDRR

:: MORE INFORMATION

Citation

J Theor Biol. 2016 Jun 7;398:122-9. doi: 10.1016/j.jtbi.2016.03.025.
Identification of WD40 repeats by secondary structure-aided profile-profile alignment.
Wang C, Dong X, Han L, Su XD, Zhang Z, Li J, Song J