HARSH (HAplotype inference using Reference and Sequencing tecHnology) is a method to infer the haplotype using haplotype reference panel and high throughput sequencing data. It is based on a novel probabilistic model and Gibbs sampler method.
SNPYGoat Software allows users of the SNPYGoat multiplex system to rapidly identify several goat Y-chromosomal haplotypes Y1A, Y1B, Y1C and Y2 by automatically comparing the obtained profile with a reference database.
HapYDive is a software for Y-STR haplotype diversity calculation.This program allows fast and reliable determination of which Y-STRs are the most informative by evaluating all possible combinations.With the HapYDive it is possible to analyse any set of Y markers up to a maximum of 20, with a minimum number of 4 markers fixed for calculations. Results on the application of this program to different population samples and sizes and with a certain combination of Y-STR markers are presented and discussed, together with its usefulness mainly to the forensic community.
HapCompass for polyploid genomes can currently be used to create accurate pairwise SNP phasings.Given a set of aligned sequence reads in a SAM file and a set of variant calls in VCF format, HAPCOMPASS will assemble reads into haplotypes.
Hapsembler is a haplotype-specific genome assembly toolkit that is designed for genomes that are rich in SNPs and other types of polymorphism. Hapsembler can be used to assemble reads from a variety of platforms including Illumina and Roche/454.
ShoRAH is a software package that allows for inference about the structure of a population from a set of short sequence reads as obtained from ultra-deep sequencing of a mixed sample. The package contains programs that support mapping of reads to a reference genome, correcting sequencing errors by locally clustering reads in small windows of the alignment, reconstructing a minimal set of global haplotypes that explain the reads, and estimating the frequencies of the inferred haplotypes.