BiasViz can be used to look at the composition of amino acids within a sliding window given a multiple sequence alignment. The window size and amino acid(s) of interest can be modified and the results are displayed in real time, allowing the user to tweak both of these parameters to their liking. The values can also be downloaded as a CSV file which allows further visualization in a separate program such as Microsoft Excel.
JOY is a program to annotate protein sequence alignments with three-dimensional (3D) structural features. It was developed to display 3D structural information in a sequence alignment and help understand the conservation of amino acids in their specific local environments. For instance, it has been recognised that a sidechain hydrogen-bonded to a main-chain amide plays an important role in stabilizing the 3D structure and is generally well conserved during evolution. Such a residue is shown in a bold-face letter in the formatted alignments. Another example is the importance of solvent inaccessible residues which are shown in UPPER-CASE letters.
BRB-ArrayTools is an integrated software package for the analysis of DNA microarray data.
BRB-ArrayTools contains utilities for processing expression data from multiple experiments, visualization of data, multidimensional scaling, clustering of genes and samples, and classification and prediction of samples. BRB-ArrayTools features drill-down linkage to NCBI databases using clone, GenBank, or UniGene identifiers, and drill-down linkage to the NetAffx database using Probeset ids.
Pyteomics is a collection of lightweight and handy tools for Python that help to handle various sorts of proteomics data. Pyteomics provides a growing set of modules to facilitate the most common tasks in proteomics data analysis
BPLA kernel (Base-pairing profile local alignment) is a powerful method that evaluates the similarity between a pair of RNAs taking into account secondary structure information. Based on the accurate similarity calculated by BPLA kernel, you can perform a broad range of structural RNA analysis, including family prediction, hierarchical clustering, and remote homology search. The method is applicable not only to classical genomic screens, but also to unannotated noncoding transcripts produced by next-generation sequencing technologies (RNA-seq).
Ontologizer is a Java webstart application for GO term enrichment analysis that provides browsing and graph visualization capabilities. The Ontologizer allows users to analyze data with the standard Fisher exact test and also the parent-child method and topology methods.
RnBeads is the first software tool that implements a comprehensive workflow for analyzing DNA methylation data in the context of large cohort studies. Its functionality comprises data normalization, quality control, probe and sample filtering, handing of batch effects, global DNA methylation analysis, detection of differentially methylated regions and interpretation by statistical enrichment analysis.