KEGGscape 0.9.1 – File Reader and Pathway Vsualizer for KEGG XML (KGML) files

KEGGscape 0.9.1

:: DESCRIPTION

KEGGscape is a pathway data integration and visualization app for Cytoscape.

::DEVELOPER

KEGGscape team

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Windows/ Linux/ MacOsX
  • Cytoscape

:: DOWNLOAD

KEGGscape

:: MORE INFORMATION

Citation

KEGGscape: a Cytoscape app for pathway data integration.
Nishida K, Ono K, Kanaya S, Takahashi K.
F1000Res. 2014 Jul 1;3:144. doi: 10.12688/f1000research.4524.1

NetworkPainter – Pathway Animation in Cytobank

NetworkPainter

:: DESCRIPTION

NetworkPainter is a web-based program for visually analyzing data stored in Cytobank. NetworkPainter enables researchers to draw signaling network diagrams and animate them with time-lapsed experimental data such as flow and mass cytometry. NetworkPainter can be used to analyze any data contained within Cytobank.

::DEVELOPER

NetworkPainter team

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Web browser

:: DOWNLOAD

 NO

:: MORE INFORMATION

Citation

NetworkPainter: dynamic intracellular pathway animation in Cytobank.
Karr JR, Guturu H, Chen EY, Blair SL, Irish JM, Kotecha N, Covert MW.
BMC Bioinformatics. 2015 May 25;16:172. doi: 10.1186/s12859-015-0602-4.

Caleydo 3.1.5 – Pathway and Gene Expression Visualization

Caleydo 3.1.5

:: DESCRIPTION

Caleydo is an open source visual analysis framework targeted at biomolecular data. The biggest strength of Caleydo is the visualization of interdependencies between multiple datasets. Caleydo can load tabular data and groupings/clusterings. You can explore relationships between multiple groupings, between different datasets and see how your data maps onto pathways.

::DEVELOPER

the Visual Data Science Lab!

:: SCREENSHOTS

:: REQUIREMENTS

  • Linux / Windows / MacOsX

:: DOWNLOAD

  Caleydo

:: MORE INFORMATION

Citation:

Bioinformatics. 2009 Oct 15;25(20):2760-1. doi: 10.1093/bioinformatics/btp432. Epub 2009 Jul 20.
Caleydo: connecting pathways and gene expression.
Streit M, Lex A, Kalkusch M, Zatloukal K, Schmalstieg D.

APP 2.30 – Pathway Viewer

APP 2.30

:: DESCRIPTION

APP (Advanced Pathway Painter)visualizes pathways (KEGG, GenMAPP, BioCarta…). The user has the possibility to display any kind of quantitative data from gene and protein experiments (e.g. microarrays from affymetrix) directly within the pathways (colours represent the value). The linking between the pathway items and the experiment data is done over the gene or protein names and their accession numbers. Furthermore the user has a quick overview on the gene/protein with the collected links in the web-interface。

::DEVELOPER

GSA

:: SCREENSHOTS

:: REQUIREMENTS

  • Windows

:: DOWNLOAD

APP

:: MORE INFORMATION

KATSURA 1.0.1 – KEGG Pathway Coverage & Expression Analysis

KATSURA 1.0.1

:: DESCRIPTION

Katsura tool is a free open source Java application designed to overlay gene expression data, comparative genomics data, or quantitative shotgun proteomics data onto metabolic pathways. Katsura uses data from the Kyoto Encyclopedia of Genes and Genomes (KEGG), Kanehisa Laboratory at Kyoto University, to build a small database containing KEGG pathway and enzyme data relating to one or more user specified organisms. Katsura manages the local database allowing users to update core information, add genomes of interest, backup the database and display database status reports. Gene expression data is input to allow visualization of pathway level expression trends over time or over a series of experimental conditions. A separate table visualizes the individual enzymes and associated gene expression values for each pathway. Capabilities such as bookmarking pathways to annotate findings, saving results to reloadable files, and the ability to output pdf reports and summary files help to capture key research findings.

::DEVELOPER

KATSURA team

:: SCREENSHOTS

:: REQUIREMENTS

  • Linux / Windows / Mac OsX
  • JAVA

:: DOWNLOAD

KATSURA

:: MORE INFORMATION

This application is released under the GPL v3 License: View License

Citation:

  1. Kanehisa, M., Goto, S., Furumichi, M., Tanabe, M., and Hirakawa, M.; KEGG for representation and analysis of molecular networks involving diseases and drugs. Nucleic Acids Res. 38, D355-D360 (2010).
  2. Kanehisa, M., Goto, S., Hattori, M., Aoki-Kinoshita, K.F., Itoh, M., Kawashima, S., Katayama, T., Araki, M., and Hirakawa, M.; From genomics to chemical genomics: new developments in KEGG. Nucleic Acids Res. 34, D354-357 (2006).
  3. Kanehisa, M. and Goto, S.; KEGG: Kyoto Encyclopedia of Genes and Genomes. Nucleic Acids Res. 28, 27-30 (2000).

FacPad 3.0 – Bayesian Sparse Factor Modeling for the Inference of Pathways responsive to Drug Treatment

FacPad 3.0

:: DESCRIPTION

FacPad is an R package implementing a Bayesian sparse factor model for the inference of pathways responsive to drug treatment.

::DEVELOPER

Zhao Hongyu’s Lab

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Windows/ Linux/MacOsX
  • R package

:: DOWNLOAD

  FacPad

:: MORE INFORMATION

Citation

Bioinformatics. 2012 Oct 15;28(20):2662-70. doi: 10.1093/bioinformatics/bts502. Epub 2012 Aug 24.
FacPad: Bayesian sparse factor modeling for the inference of pathways responsive to drug treatment.
Ma H, Zhao H.

MetaMapR 1.4 – Pathway Independent Metabolomic Network Analysis Incorporating Unknowns

MetaMapR 1.4

:: DESCRIPTION

MetaMapR integrates enzymatic transformations with metabolite structural similarity, mass spectral similarity and empirical associations to generate richly connected metabolic networks.

::DEVELOPER

Dmitry Grapov

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Linux/ Windows
  • R

:: DOWNLOAD

 MetaMapR

:: MORE INFORMATION

Citation

MetaMapR: Pathway Independent Metabolomic Network Analysis Incorporating Unknowns.
Grapov D, Wanichthanarak K, Fiehn O.
Bioinformatics. 2015 Apr 5. pii: btv194.

pwOmics 1.24.0 – Pathway-based data integration of Omics data

pwOmics 1.24.0

:: DESCRIPTION

pwOmics performs pathway-based level-specific data comparison of matching omics data sets based on pre-analysed user-specified lists of differential genes/transcripts and proteins.

::DEVELOPER

Astrid Wachter <Astrid.Wachter at med.uni-goettingen.de>

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Windows/Linux/MacOsX
  • R
  • BioConductor

:: DOWNLOAD

 pwOmics

:: MORE INFORMATION

Citation

pwOmics: An R package for pathway-based integration of time-series omics data using public database knowledge.
Wachter A, Beissbarth T.
Bioinformatics. 2015 May 21. pii: btv323.

KEGGgraph 1.52.0 – A Graph Approach to KEGG PATHWAY in R and Bioconductor

KEGGgraph 1.52.0

:: DESCRIPTION

KEGGGraph is an interface between KEGG pathway and graph object as well as a collection of tools to analyze, dissect and visualize these graphs. It parses the regularly updated KGML (KEGG XML) files into graph models maintaining all essential pathway attributes. The package offers functionalities including parsing, graph operation, visualization and etc.

::DEVELOPER

Jitao David Zhang <jitao_david.zhang at roche.com>, Stefan Wiemann 

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Windows / Linux/ MacOsX
  • R
  • BioConductor

:: DOWNLOAD

 KEGGgraph

:: MORE INFORMATION

Citation

Bioinformatics. 2009 Jun 1;25(11):1470-1. doi: 10.1093/bioinformatics/btp167. Epub 2009 Mar 23.
KEGGgraph: a graph approach to KEGG PATHWAY in R and bioconductor.
Zhang JD, Wiemann S.

MEPSA 1.4 – Minimum Energy Pathway Analysis for Energy Landscapes

MEPSA 1.4

:: DESCRIPTION

MEPSA is a cross-platform user friendly tool for the analysis of energy landscapes from a transition state theory perspective.

::DEVELOPER

Molecular Modelling Group

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Linux / Windows / MacOsX
  • Python

:: DOWNLOAD

 MEPSA

:: MORE INFORMATION

Citation

MEPSA: minimum energy pathway analysis for energy landscapes.
Marcos-Alcalde I, Setoain J, Mendieta-Moreno JI, Mendieta J, Gómez-Puertas P.
Bioinformatics. 2015 Jul 31. pii: btv453.