CNT-MD – Coordinate-descent algorithm for the Copy-Number Tree Mixture Deconvolution

CNT-MD

:: DESCRIPTION

CNT-MD is a software for inferring the copy-number profiles of tumor clones and their evolution from fractional copy numbers obtained from multi-sample bulk sequencing data.

::DEVELOPER

Raphael Lab

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Linux

:: DOWNLOAD

CNT-MD

:: MORE INFORMATION

Citation:

Simone Zaccaria, Mohammed El-Kebir, Gunnar W. Klau, Benjamin J. Raphael:
The Copy-Number Tree Mixture Deconvolution Problem and Applications to Multi-sample Bulk Sequencing Tumor Data.
RECOMB 2017: 318-335

SBT / SSBT 0.1 – (Split) Sequence Bloom Tree

SBT / SSBT 0.1

:: DESCRIPTION

The SBT (Sequence Bloom Tree) is a method that will allow you to index a set of short-read sequencing experiments and then query them quickly for a given sequence

SSBT is a method that will allow you to index a set of short-read sequencing experiments and then query them quickly for a given sequence.

::DEVELOPER

Kingsford Group

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Linux / MacOs
  • GCC
  • Jellyfish

:: DOWNLOAD

SBT / SSBT

:: MORE INFORMATION

Citation

Brad Solomon, Carl Kingsford (2016).
Fast search of thousands of short-read sequencing experiments.
Nature Biotechnology 34:300-302.

J Comput Biol. 2018 Jul;25(7):755-765. doi: 10.1089/cmb.2017.0265. Epub 2018 Mar 12.
Improved Search of Large Transcriptomic Sequencing Databases Using Split Sequence Bloom Trees.
Solomon B, Kingsford C

SHOT 2.0 – Shared Ortholog and Gene Order Tree Reconstruction Tool

SHOT 2.0

:: DESCRIPTION

SHOT is a web server for the classification of genomes on the basis of shared gene content or the conservation of gene order that reflects the dominant, phylogenetic signal in these genomic properties. In general, the genome trees are consistent with classical gene-based phylogenies, although some interesting exceptions indicate massive horizontal gene transfer. SHOT is a useful tool for analysing the tree of life from a genomic point of view

::DEVELOPER

Bork Group

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Web Browser

:: DOWNLOAD

  NO

:: MORE INFORMATION

Citation

SHOT: a web server for the construction of genome phylogenies.
Korbel JO, Snel B, Huynen MA, Bork P
Trends Genet. 2002 Mar; 18(3): 158-62. PubMed: 11858840.

SimCopy 0.2 – Simulate the Evolution of Copy Number Profiles along a Tree

SimCopy 0.2

:: DESCRIPTION

SimCopy is an R package simulating the evolution of copy number profiles along a tree. It relies on the PhyloSim package for performing the simulations by encoding the genomic regions as sites in sequences and using modified processes acting on them.

::DEVELOPER

Botond Sipos

:: REQUIREMENTS

:: DOWNLOAD

 SimCopy

:: MORE INFORMATION

Serial NetEvolve 1.0 – A flexible utility for generating serially-sampled Sequences along a Tree or Recombinant Network

Serial NetEvolve 1.0

:: DESCRIPTION

Serial NetEvolve is a modification of the Treevolve program in which serially sampled sequences are evolved along a randomly generated coalescent tree or network (Grassly et al. 1999; Hudson 1983; Kingman 1982) . Treevolve offers a variety of evolutionary model and population parameters including a rate of recombination and as such it was chosen over other programs to be adapted for the simulation of serially sampled data. The new features include the choice of either a clock-like model of evolution or a variable rate of evolution, simulation of serial samples and the output of the randomly generated tree or network in Newick format or in our newly formulated NeTwick format.

::DEVELOPER

Bioinformatics Research Group (BioRG)

:: SCREENSHOTS

SerialNetEvolve

:: REQUIREMENTS

  • Linux / Windows / MacOsX
  • C Compiler

:: DOWNLOAD

 Serial NetEvolve

:: MORE INFORMATION

Citation:

Bioinformatics. 2006 Sep 15;22(18):2313-4. Epub 2006 Jul 14.
Serial NetEvolve: a flexible utility for generating serially-sampled sequences along a tree or recombinant network.
Buendia P, Narasimhan G.

Peditree 2005 – Plant Pedigree Tree Drawing & Analysis

Peditree 2005

:: DESCRIPTION

PediTree is a software package to recursively analyse plant pedigree data which is arranged in a simple-single table database structure.

Peditree will lookup the parents of a variety/cultivar, then the parents of the parents (grandparents)and so on. The result is displayed in a explorer style, collapsible tree or a pedigree drawing (see images below; click to enlarge).

::DEVELOPER

Wageningen UR Plant Breeding

:: SCREENSHOTS

:: REQUIREMENTS

  • Windows

:: DOWNLOAD

Peditree

:: MORE INFORMATION

Citation

J Hered. 2005 Jul-Aug;96(4):465-8. Epub 2005 Apr 13.
Peditree: pedigree database analysis and visualization for breeding and science.
van Berloo R, Hutten RC.

phyutility 2.6 – Phyloinformatic Utility for Trees, Alignments, and Molecular data

phyutility 2.6

:: DESCRIPTION

phyutility (Phyloinformatic utility) is a Java program to perform simple but essential tasks on sequences and trees from the command line.

::DEVELOPER

STEPHEN A. SMITH

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Windows / Linux / Mac OsX
  • Java

:: DOWNLOAD

 phyutility

:: MORE INFORMATION

Citation

Smith, S. A. and Dunn, C. W. (2008)
Phyutility: a phyloinformatics tool for trees, alignments, and molecular data.
Bioinformatics. 24: 715-716

TAXNAMECONVERT 2.4 – Rename Sequence and Taxon names in Tree and Sequence files

TAXNAMECONVERT 2.4

:: DESCRIPTION

Taxnameconvert is a commandline software that takes as input a file with a name table and usually a Newick formatted tree file or fasta sequence/alignment file, but can also be used to exchange names in many other text file formats.

::DEVELOPER

 the Center of Integrative Bioinformatics Vienna (CIBIV) headed by Arndt von Haeseler.

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Linux / WIndows /MacOsX
  • Perl

:: DOWNLOAD

 Taxnameconvert

:: MORE INFORMATION

GeoMeTree 1.1 – Geodesic Metric on Trees

GeoMeTree 1.1

:: DESCRIPTION

GeoMeTree is a python program to compute the geodesic path between two phylogenetic trees.

::DEVELOPER

 the Center of Integrative Bioinformatics Vienna (CIBIV) headed by Arndt von Haeseler.

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Linux / Windows / MacOsX
  • Python

:: DOWNLOAD

 GeoMeTree

:: MORE INFORMATION

Citation:

J Comput Biol. 2008 Jul-Aug;15(6):577-91.
An exact algorithm for the geodesic distance between phylogenetic trees.
Kupczok A, Haeseler AV, Klaere S.