OAT 0.91 – Similarity Measurement Tool for Genomes

OAT 0.91

:: DESCRIPTION

OAT (Orthologous Average Nucleotide Identity Tool) uses OrthoANI to measure overall similarity between two genome sequences.

::DEVELOPER

OAT team

:: SCREENSHOTS

OAT

:: REQUIREMENTS

  • Linux / MacOsX / Windows
  • Java

:: DOWNLOAD

 OAT

:: MORE INFORMATION

Citation:

OrthoANI: An improved algorithm and software for calculating average nucleotide identity.
Lee I, Kim YO, Park SC, Chun J.
Int J Syst Evol Microbiol. 2015 Nov 18. doi: 10.1099/ijsem.0.000760.

GeneExpressionSignature 1.38.0 – Gene Expression Signature based Similarity Metric

GeneExpressionSignature 1.38.0

:: DESCRIPTION

GeneExpressionSignature gives the implementations of the gene expression signature and its distance to each. Gene expression signature is represented as a list of genes whose expression is correlated with a biological state of interest. And its distance is defined using a nonparametric, rank-based pattern-matching strategy based on the Kolmogorov-Smirnov statistic. Gene expression signature and its distance can be used to detect similarities among the signatures of drugs, diseases, and biological states of interest.

::DEVELOPER

Yang Cao <yiluheihei at gmail.com>, Fei Li <pittacus at gmail.com>,Lu Han <hanl8910 at gmail.com>

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Linux /Windows/ MacOsX
  • R
  • BioConductor

:: DOWNLOAD

 GeneExpressionSignature

:: MORE INFORMATION

Citation

OMICS. 2013 Feb;17(2):116-8. doi: 10.1089/omi.2012.0087.
GeneExpressionSignature: an R package for discovering functional connections using gene expression signatures.
Li F1, Cao Y, Han L, Cui X, Xie D, Wang S, Bo X.

MicroPattern – Microbe Set Enrichment Analysis and Disease Similarity Calculation

MicroPattern

:: DESCRIPTION

MicroPattern is a tool used to mine regular rules and patterns behind a list of microbes. MicroPattern can also be used to calculate the similarity between the given disease-associated microbe list and the collected micro-disease association dataset

::DEVELOPER

the Cui Lab

:: SCREENSHOTS

n/a

:: REQUIREMENTS

  • Web browser

:: DOWNLOAD

 NO

:: MORE INFORMATION

Citation

Ma W, Huang C, Zhou Y, Li J, Cui Q.
MicroPattern: a web-based tool for microbe set enrichment analysis and disease similarity calculation based on a list of microbes.
Sci Rep. 2017 Jan 10;7:40200. doi: 10.1038/srep40200. PMID: 28071710; PMCID: PMC5223220.

GOGO – Measure Semantic Similarity between Gene Ontology terms

GOGO

:: DESCRIPTION

GOGO is an improved algorithm to measure the semantic similarity of gene ontology terms

::DEVELOPER

Z. WANG LAB

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Linux
  • Perl

:: DOWNLOAD

GOGO

:: MORE INFORMATION

Citation

Zhao C, Wang Z.
GOGO: An improved algorithm to measure the semantic similarity between gene ontology terms.
Sci Rep. 2018 Oct 10;8(1):15107. doi: 10.1038/s41598-018-33219-y. PMID: 30305653; PMCID: PMC6180005.

PSS 20091105 – Protein Profile Similarity Screening

PSS 20091105

:: DESCRIPTION

PSS is a matlab code of computational protein profile similarity screening for quantitative mass spectrometry experiments.

::DEVELOPER

Hamprecht lab

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Linux / Windows/ MacOsX
  • MatLab

:: DOWNLOAD

 PSS

:: MORE INFORMATION

Citation

Bioinformatics. 2010 Jan 1;26(1):77-83. doi: 10.1093/bioinformatics/btp607. Epub 2009 Oct 27.
Computational protein profile similarity screening for quantitative mass spectrometry experiments.
Kirchner M1, Renard BY, Köthe U, Pappin DJ, Hamprecht FA, Steen H, Steen JA.

Csbl.go 1.4.1 – Gene Ontology based Clustering using semantic Similarity

Csbl.go 1.4.1

:: DESCRIPTION

Csbl.go is an R package for computing semantic similarity between genes using Gene Ontology annotation and for clustering genes based on the similarity measures. The package also includes GO enrichment analysis functionality.

::DEVELOPER

Hautaniemi Lab

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Windows/Linux/MacOsX
  • R Package

:: DOWNLOAD

 Csbl.go

:: MORE INFORMATION

Citation

Fast Gene Ontology based clustering for microarray experiments
Kristian Ovaska, Marko Laakso and Sampsa Hautaniemi
BioData Mining 2008, 1:11

TM-score 20190822 – Calculate Similarity of Topologies of two Protein Structures

TM-score 20190822

:: DESCRIPTION

TM-score is an algorithm to calculate the similarity of topologies of two protein structures. It can be exploited to quantitatively access the quality of protein structure predictions relative to native. Because TM-score weights the close matches stronger than the distant matches, TM-score is more sensitive than root-mean-square deviation (RMSD)

::DEVELOPER

Yang Zhang’s Research Group

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Linux
:: DOWNLOAD

 TM-score

:: MORE INFORMATION

Citation

J. Xu, Y. Zhang,
How significant is a protein structure similarity with TM-score=0.5?
Bioinformatics, 2010 26, 889-895

IntervalStats – Statistical Evaluation of ChIPseq Dataset Similarity

IntervalStats

:: DESCRIPTION

IntervalStats is an effective statistical evaluation of ChIPseq dataset similarity.

::DEVELOPER

Chikina Lab

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Linux
  • C Compiler

:: DOWNLOAD

 IntervalStats

:: MORE INFORMATION

Citation

Bioinformatics. 2012 Mar 1;28(5):607-13. doi: 10.1093/bioinformatics/bts009.
An effective statistical evaluation of ChIPseq dataset similarity.
Chikina MD, Troyanskaya OG.

GS-align – Glycan Structure Alignment and Similarity Measurement

GS-align

:: DESCRIPTION

GS-align is a novel computational method for glycan structure alignment and similarity measurement. GS-align generates possible alignments between two glycan structures through iterative maximum clique search and fragment superposition, and the optimal alignment is determined by the maximum structural similarity score, GS-score whose significance is size-independent.

::DEVELOPER

Wonpil Im Research Group

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Linux
  • C++ Compiler

:: DOWNLOAD

 GS-align

:: MORE INFORMATION

Citation

GS-align for Glycan Structure Alignment and Similarity Measurement.
Lee HS, Jo S, Mukherjee S, Park SJ, Skolnick J, Lee J, Im W.
Bioinformatics. 2015 Apr 8. pii: btv202

ASSIST v1- Active Site Similarity Search Tool

ASSIST v1

:: DESCRIPTION

ASSIST is an application for the detection of catalytic sites in unknown function proteins.

::DEVELOPER

the Theoretical Biology and Bioinformatics Laboratory

:: SCREENSHOTS

N/A

::REQUIREMENTS

  • Windows/Linux
  • JRE

:: DOWNLOAD

  ASSIST

:: MORE INFORMATION

Citation

Bioinformatics. 2014 Apr 1;30(7):1022-4. doi: 10.1093/bioinformatics/btt664. Epub 2013 Nov 15.
ASSIST: a fast versatile local structural comparison tool.
Caprari S, Toti D, Viet Hung L, Di Stefano M, Polticelli F.