Tag: Prioritize

DPS 1.4.0 – Predict and Prioritize Pairs of Drugs

DPS 1.4.0

:: DESCRIPTION

DPS (Drug Pair Seeker) is a Java program that attempts to predict and prioritize pairs of drugs using the Connectivity Map dataset. Users can enter lists of up and down differentially expressed genes from their experiments to receive a ranked list of drug combinations that are predicted to either reverse or aggravate the gene expression state of the cells or tissue of interest using a simple formula.

::DEVELOPER

Ma’ayan Laboratory

:: SCREENSHOTS

dps1

:: REQUIREMENTS

  • Windows/Linux/MacOsX
  • Java 

:: DOWNLOAD

 DPS

:: MORE INFORMATION

Citation

Zhong Y, Chen EY, Liu R, Chuang PY, Mallipattu SK, Tan CM, Clark NR, Deng Y, Klotman PE, Ma’ayan A, He JC.
Renoprotective effect of combined inhibition of angiotensin-converting enzyme and histone deacetylase.
J Am Soc Nephrol. 2013 Apr;24(5):801-11

PS_SNP – Prioritize and Select SNPs for Whole Genome Association Studies with Two-stage Designs

PS_SNP

:: DESCRIPTION

PS_SNP is a novel SNP selection procedure for whole genome association studies with two-stage designs.

::DEVELOPER

Jing Li

:: SCREENSHOTS

N/A

:: REQUIREMENTS

:: DOWNLOAD

 PS_SNP

:: MORE INFORMATION

Citation

Jing Li.
Prioritize and select SNPs for association studies with multi-stage designs.
J Comput Biol. 2008 Apr;15(3):241-57.

CGI – Prioritize Genes by Integrating Expression data and Protein Interaction data

CGI

:: DESCRIPTION

CGI (Combining Gene expression and protein Interaction data) is intended to implement a new approach to prioritize genes by integrating expression data and protein interaction data.

::DEVELOPER

Fengzhu Sun

:: SCREENSHOTS

N/A

:: REQUIREMENTS

:: DOWNLOAD

 CGI

:: MORE INFORMATION

Citation

Ma XT, Lee HJ, Wang L, and Sun FZ
CGI: a new approach for prioritizing genes by Combining Gene expression and protein-protein Interaction data
Bioinformatics (2007) 23 (2): 215-221.