imappingfamily – QTL Detection in a Population with Family Structure

imappingfamily

:: DESCRIPTION

 imappingfamily is a package with a graphical interface regrouping the different methods presented in the article submitted “Quantitative Trait Locus Detection in a population with family structure”.

::DEVELOPER

Charles-Elie Rabier

:: SCREENSHOTS

:: REQUIREMENTS

  • Linux/windows / MacOsX
  • Matlab

:: DOWNLOAD

 imappingfamily

:: MORE INFORMATION

Citation

Rabier C-E, Azais J-M, Elsen J-M, Delmas C.
Quantitative Trait Locus Detection in a population with family structure
(submitted)

SENDBS – Computes Average Nucleotide Substitutions within and between Populations

SENDBS

:: DESCRIPTION

SENDBS computes average nucleotide substitutions within and between populations with standard errors of average nucleotide substitutions estimated with a bootstrap method by resampling sites. Also constructs a population tree with a neighbor-joining method.

::DEVELOPER

Naoko Takezaki

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Windows

:: DOWNLOAD

  SENDBS

:: MORE INFORMATION

Citation:

Mol Biol Evol. 1989 May;6(3):290-300.
Variances of the average numbers of nucleotide substitutions within and between populations.
Nei M, Jin L.

WhichRun 4.1 – software for Assigning Individuals to Populations

WhichRun 4.1

:: DESCRIPTION

WhichRun is a computer program for population assignment of individuals based on multilocus genotype data.

::DEVELOPER

Michael A. Banks and Will Eichert  @ MFGL
BODEGA MARINE LABORATORY ,

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Windows

:: DOWNLOAD

 WhichRun 

:: MORE INFORMATION

Citation:

Banks, M.A. and W. Eichert. 2000.
WHICHRUN (Version 3.2) a computer program for population assignment of individuals based on multilocus genotype data.
Journal of Heredity. 91:87-89.

StreamTree 20090303 – Map Genetic Differences between Populations

StreamTree 20090303

:: DESCRIPTION

StreamTree estimates how much each section of a river contributes to the genetic differentiation among populations.

::DEVELOPER

Steven Kalinowski, Ph.D.

:: SCREENSHOTS

N/A

::REQUIREMENTS

:: DOWNLOAD

  StreamTree

:: MORE INFORMATION

Citation

Kalinowski ST, MH Meeuwig, SR Narum, ML Taper (2008)
Stream trees: a statistical method for mapping genetic differences between populations of freshwater organisms to the sections of streams that connect them.
Canadian Journal of Fisheries and Aquatic Sciences (65:2752-2760).

MM-Dist 20070306 – Estimating the Distribution of Genotypic Differences (mismatches) between Individuals in a Population

MM-Dist 20070306

:: DESCRIPTION

MM-DIST is a computer program that calculates probability distributions for how many loci individuals in a population will differ by. For example, the graph below shows the probability of two individuals differing (mismatching) by 0 to 10 loci for unrelated individuals (solid line) and full siblings (dashed line) in a population of bighorn sheep.

::DEVELOPER

Steven Kalinowski, Ph.D.

:: SCREENSHOTS

N/A

::REQUIREMENTS

:: DOWNLOAD

 MM-Dist

:: MORE INFORMATION

Citation

Kalinowski ST, M Sawaya, ML Taper (2006)
Individual identification and distributions of genotypic differences.
Journal of Wildlife Management 70:148-150.

Margarita – Infer Genealogies from Population Genotype data

Margarita

:: DESCRIPTION

Margarita infers genealogies from population genotype data and uses these to map disease loci.

::DEVELOPER

Richard Durbin.

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Linux / MacOsX / Windows
  • Java

:: DOWNLOAD

 Margarita

:: MORE INFORMATION

Citation

Mapping trait loci by use of inferred ancestral recombination graphs.
Minichiello MJ and Durbin R
American journal of human genetics2006;79;5;910-22

ROADTRIPS 1.2 – Case-Control Association Testing with Partially or Completely Unknown Population and Pedigree Structure

ROADTRIPS 1.2

:: DESCRIPTION

ROADTRIPS is a C program that performs single-SNP, case-control association testing in samples with partially or completely unknown population and pedigree structure.ROADTRIPS uses an empirical covariance matrix calculated from genomewide SNP data to correct for unknown population and pedigree structure, while maintaining high power by taking advantage of known pedigree information when it is available. The program is applicable to association studies with completely general combinations of related and unrelated individuals. Analysis can be performed genomewide (currently just for autosomes).

::DEVELOPER

Timothy Thornton and Mary Sara McPeek

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Linux /  Windows / MacOsX
  • C Compier

:: DOWNLOAD

 ROADTRIPS 

:: MORE INFORMATION

Citation

Thornton T., McPeek M. S.
ROADTRIPS: Case-Control Association Testing with Partially or Completely Unknown Population and Pedigree Structure” (2010)
American Journal of Human Genetics, vol 86, pp. 172-184.

Overpaint 0.2 – Joint Estimation of Gene Conversion Rates and Mean Conversion Tract Lengths from Population SNP data

Overpaint 0.2

:: DESCRIPTION

Overpaint is a C++ package that can jointly estimate crossover rates, gene conversion rates and mean conversion tract lengths from population SNP dataset.

::DEVELOPER

Yun S. Song

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Linux /MacOsX
  • gsl

:: DOWNLOAD

 Overpaint

:: MORE INFORMATION

Citation

Yin, J. Jordan, M. I., and Song, Y. S..
Joint estimation of gene conversion rates and mean conversion tract lengths from population SNP data,
Bioinformatics, 25 (2009) i231-i239

SelSim 2.1 – Simulate Population Genetic Data with Selection and Recombination

SelSim 2.1

:: DESCRIPTION

SelSim is a program for Monte Carlo simulation of DNA polymorphism data for a recombining region within which a single bi-allelic site has experienced natural selection. SelSim allows simulation from either a fully stochastic model of, or deterministic approximations to, natural selection within a coalescent framework. A number of different mutation models are available for simulating surrounding neutral variation. The package enables a detailed exploration of the effects of different models and strengths of selection on patterns of diversity.

::DEVELOPER

Chris C A Spencer

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Linux/WIndows

:: DOWNLOAD

 SelSim

:: MORE INFORMATION

Citation

Spencer C., Coop, G. (2005)
SelSim: A program to simulate population genetic data with selection and recombination.
Bioinformatics. 2004 Dec 12;20(18):3673-5.

TetraploidMap 1.0.6 – Calculate Linkage Maps for Autotetraploid Populations

TetraploidMap 1.0.6

:: DESCRIPTION

TetraploidMap is a graphical user interface for calculating linkage maps for autotetraploid populations. It is suitable for handling markers scored on two parents and the full-sib offspring of a cross between them. TetraploidMap handles both codominant and dominant molecular markers, in all possible configurations, and takes into account the presence of null alleles in the analysis. It now includes a routine for QTL mapping.

::DEVELOPER

Christine Hackett at Biomathematics and Statistics Scotland (BioSS)

:: SCREENSHOTS

:: REQUIREMENTS

  • Windows

:: DOWNLOAD

 TetraploidMap

:: MORE INFORMATION

Citation

Hackett, C.A.Milne, I., Bradshaw, J.E. & Luo, Z.W. 2007.
TetraploidMap for Windows: linkage map construction and QTL mapping in autotetraploid species.
Journal of Heredity 98, 727-729.