MimicrEE – Simulating Genotypes and Phenotypes in experimentally evolving populations

MimicrEE

:: DESCRIPTION

MimicrEE (Mimicing Experimental Evolution) is a tool for forward simulations of entire genomes. It basically allowes to simulate adaptation from standing genetic variation, thus no ‘de novo’ mutations are supported. It has been tested with 8,000 individulas having 2,000,000 million SNPs.

DEVELOPER

Institute of Population Genetics, University of Veterinary Medicine Vienna

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Linux / MacOsX / Windows
  • Java

:: DOWNLOAD

MimicrEE

:: MORE INFORMATION

SLiM 3.3.1 – Forward Population Genetic Simulation

SLiM 3.3.1

:: DESCRIPTION

SLiM (Selection on Linked Mutations) is an evolutionary simulation framework that combines a powerful engine for population genetic simulations with the capability of modeling arbitrarily complex evolutionary scenarios. Simulations are configured via the integrated Eidos scripting language that allows interactive control over practically every aspect of the simulated evolutionary scenarios.

::DEVELOPER

Messer Lab

:: SCREENSHOTS

:: REQUIREMENTS

  • MacOsX
:: DOWNLOAD

SLiM

:: MORE INFORMATION

Citation

SLiM 3: Forward Genetic Simulations Beyond the Wright-Fisher Model.
Haller BC, Messer PW.
Mol Biol Evol. 2019 Mar 1;36(3):632-637. doi: 10.1093/molbev/msy228.

PSIKO v2 – Infer Population Stratification on various levels in GWAS

PSIKO v2

:: DESCRIPTION

PSIKO (Population Structure Inference using Kernel-pca and Optimisation) is a software tool written in C++ for quick and accurate estimation of individual ancestry coefficients of a dataset exhibiting population structure.

::DEVELOPER

The UEA Computational Biology Laboratory at the University of East Anglia (UEA)

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Linux
  • g++

:: DOWNLOAD

PSIKO

:: MORE INFORMATION

Citation

PSIKO2: a fast and versatile tool to infer population stratification on various levels in GWAS.
Popescu AA, Huber KT.
Bioinformatics. 2015 Jul 2. pii: btv396.

SANTA-SIM 1.0 – Simulate the Evolution of Population of Gene Sequences Forwards through Time

SANTA-SIM 1.0

:: DESCRIPTION

SANTA-SIM is a forward-time simulator for gene sequences modeling a variety of mutation and selection processes.

::DEVELOPER

SANTA-SIM team

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Windows / Linux / MacOS
  • Java

:: DOWNLOAD

SANTA-SIM

:: MORE INFORMATION

Citation:

SANTA-SIM: simulating viral sequence evolution dynamics under selection and recombination.
Jariani A, Warth C, Deforche K, Libin P, Drummond AJ, Rambaut A, Matsen Iv FA, Theys K.
Virus Evol. 2019 Mar 8;5(1):vez003. doi: 10.1093/ve/vez003.

ngsTools 1.0.2 – Population Genetics Analyses from Next-generation Sequencing data

ngsTools 1.0.2

:: DESCRIPTION

ngsTools is a collection of programs for population genetics analyses from NGS data, taking into account data statistical uncertainty.

::DEVELOPER

ngsTools team

:: SCREENSHOTS

:: REQUIREMENTS

  • Linux
  • R

:: DOWNLOAD

ngsTools

:: MORE INFORMATION

Citation

ngsTools: methods for population genetics analyses from next-generation sequencing data.
Fumagalli M, Vieira FG, Linderoth T, Nielsen R.
Bioinformatics. 2014 May 15;30(10):1486-7. doi: 10.1093/bioinformatics/btu041.

Genepop 4.5 – Population Genetics Software Package

Genepop 4.5

:: DESCRIPTION

GENEPOP is a population genetics software package

::DEVELOPER

Michel Raymond (Raymond@isem.univ-montp2.fr) and Francois Rousset (Rousset@isem.univ-montp2.fr)

:: SCREENSHOTS

N/A

::REQUIREMENTS

  • Linux  / Windows

:: DOWNLOAD

 Genepop

:: MORE INFORMATION

Citation

Rousset, F., 2008.
Genepop’007: a complete reimplementation of the Genepop software for Windows and Linux.
Mol. Ecol. Resources 8: 103-106.

GONe 1.03 – Estimating Effective size (Ne) in Populations with Overlapping Generations

GONe 1.03

:: DESCRIPTION

GONe (Generational Overlap Ne) is a user-friendly, Windows-based program for estimating effective size (Ne) in populations with overlapping generations. It uses the Jorde-Ryman modification to the temporal method to account for age-structure in populations.

::DEVELOPER

Jason Coombs ,jcoombs@cns.umass.edu ,Ben Letcher, and Keith Nislow

:: SCREENSHOTS

GONe

:: REQUIREMENTS

  • Windows 

:: DOWNLOAD

 GONe

:: MORE INFORMATION

Citation

GONe: software for estimating effective population size in species with generational overlap.
Coombs JA, Letcher BH, Nislow KH.
Mol Ecol Resour. 2012 Jan;12(1):160-3. doi: 10.1111/j.1755-0998.2011.03057.x

DistMiss 1.0 – Compute Matrix of Genetic Distances between Populations

DistMiss 1.0

:: DESCRIPTION

DistMiss computes a matrix of genetic distances between populations on the basis of their allele frequencies at L loci.

::DEVELOPER

DistMiss Team

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Linux / Windows
  • Fortran

:: DOWNLOAD

 DistMiss

:: MORE INFORMATION

MDIV – Estimate Divergence Times and Migration Rates between two Populations

MDIV

:: DESCRIPTION

MDIV is a program that will simultaneously estimate divergence times and migration rates between two populations under the infinite sites model and under a finite sites model (HKY). The program can be used to test if there is evidence for migration between two populations or evidence for shared recent common ancestry. In addition, you get maximum likelihood estimates of the demographic parameters.

::DEVELOPER

the Nielsen group

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Windows

:: DOWNLOAD

 MDIV

:: MORE INFORMATION

Citation:

Genetics. 2001 Jun;158(2):885-96.
Distinguishing migration from isolation: a Markov chain Monte Carlo approach.
Nielsen R, Wakeley J.

ProSeq 3.5 – Sequence Editing and Population Genetics Analysis

ProSeq 3.5

:: DESCRIPTION

ProSeq (PROcessor of SEQuences) is a program for sequence editing and population genetics (mol/evol) analysis.ProSeq is quite a convenient tool for sequence handling (correcting ABI chromatograms, contig assembly, hand correction of the alignments etc.) and preliminary molecular evolution analysis. However, it is recommended to check the results of the analyses by the other software since the program is under development and not all the parts of the program are thoroughly tested and completely reliable

::DEVELOPER

Dr. Dmitry Filatov

:: SCREENSHOTS

:: REQUIREMENTS

  • Windows / Linux

:: DOWNLOAD

ProSeq

:: MORE INFORMATION

Citation

Filatov, D.A. (2009)
Processing and population genetic analysis of multigenic datasets with ProSeq3 software
Bioinformatics. 25 (23): pp 3189-3190.