GenomeLaser – Haplotyping from Pedigree Genotypes

GenomeLaser 1.5

:: DESCRIPTION

GenomeLaser is a tool for haplotype inference from pedigree genotypes.

::DEVELOPER

GenomeLaser team

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Linux
  • Python

:: DOWNLOAD

 GenomeLaser

:: MORE INFORMATION

Citation

GenomeLaser: fast and accurate haplotyping from pedigree genotypes.
Li W, Fu G, Rao W, Xu W, Ma L, Guo S, Song Q.
Bioinformatics. 2015 Aug 18. pii: btv452.

GenotypeChecker 1.005 – Checking the Inheritance Consistency of Pedigree/Genotype Data

GenotypeChecker 1.005

:: DESCRIPTION

Roslin’s ResSpecies GenotypeChecker is a desktop tool for identifying likely data errors in pedigree/genotype datasets and to assist data cleansing.

::DEVELOPER

Roslin Bioinformatics

:: SCREENSHOTS

GenotypeChecker

:: REQUIREMENTS

  • Linux/MacOsX / Windows
  • Java

:: DOWNLOAD

 GenotypeChecker 

:: MORE INFORMATION

Citation

Anim Genet. 2011 Oct;42(5):560-2. doi: 10.1111/j.1365-2052.2011.02183.x. Epub 2011 Mar 24.
Genotypechecker: an interactive tool for checking the inheritance consistency of genotyped pedigrees.
Paterson T, Law A.

nucular 20050222 – Splits Extended Pedigrees into Nuclear Families

nucular 20050222

:: DESCRIPTION

nucular is a program that splits extended pedigrees into nuclear families, with the option of recoding all sibs as half-sibs with distinct mothers of fathers.

::DEVELOPER

Mathieu Lemire

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Linux
  • C Compiler

:: DOWNLOAD

  nucular

:: MORE INFORMATION

Citation

BMC Genet. 2005 Dec 30;6 Suppl 1:S159.
A simple nonparametric multipoint procedure to test for linkage through mothers or fathers as well as imprinting effects in the presence of linkage.
Lemire M.

SPIP 1.0 – Simulate Pedigrees and Genetic data in Age-structured Population

SPIP 1.0

:: DESCRIPTION

SPIP (simulate pedigrees in populations) simulates the transmission of genes from parents to offspring in a population having demographic structure defined by the user. Numerous variables controlling the age structure of the population, the number of offspring produced, the variance in male and female reproductive success, survival rates of different age classes, mate fidelity, duration of simulation, etc. can be specified by the user.

::DEVELOPER

Eric C. Anderson

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Windows / Linux / MacOsX

:: DOWNLOAD

 SPIP

:: MORE INFORMATION

Citation

Anderson, E. C., and K. K. Dunham.2005.
SPIP 1.0: a program for simulating pedigrees and genetic data in age-structured populations.
Molecular Ecology Notes 5(2):459-461.

FRANz 2.0 – Reconstruction of Pedigrees

FRANz 2.0

:: DESCRIPTION

FRANz is a fast and flexible parentage inference program for natural populations.

::DEVELOPER

Bioinformatics Leipzig

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Linux/windows/MacOsX

:: DOWNLOAD

 FRANz

:: MORE INFORMATION

Citation

FRANz: Reconstruction of wild multi-generation pedigrees.
Markus Riester, Peter F Stadler, Konstantin Klemm.
Bioinformatics. 2009. 25:2134-2139.

Peditree 2005 – Plant Pedigree Tree Drawing & Analysis

Peditree 2005

:: DESCRIPTION

PediTree is a software package to recursively analyse plant pedigree data which is arranged in a simple-single table database structure.

Peditree will lookup the parents of a variety/cultivar, then the parents of the parents (grandparents)and so on. The result is displayed in a explorer style, collapsible tree or a pedigree drawing (see images below; click to enlarge).

::DEVELOPER

Wageningen UR Plant Breeding

:: SCREENSHOTS

:: REQUIREMENTS

  • Windows

:: DOWNLOAD

Peditree

:: MORE INFORMATION

Citation

J Hered. 2005 Jul-Aug;96(4):465-8. Epub 2005 Apr 13.
Peditree: pedigree database analysis and visualization for breeding and science.
van Berloo R, Hutten RC.

PedigreeSim – Simulation of Genotypes in Pedigrees of Diploid and Tetraploid Species

PedigreeSim

:: DESCRIPTION

PedigreeSim is software that generates simulated genetic marker data of individuals in pedigreed populations. A population can consist of either diploid or tetraploid individuals. PedigreeSim can simulate meioses with or without chiasma interference, and in tetraploids it can simulate meioses with two bivalents or one quadrivalent per set of hom(oe)ologous chromosomes. Also varying probabilities of preferential versus random pairing of chromosomes can be simulated, allowing to simulate amphidiploids as well as autotetraploids and intermediate forms.

::DEVELOPER

Wageningen UR Plant Breeding

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Windows/ MacOsX / Linux
  • Java

:: DOWNLOAD

 PedigreeSim

:: MORE INFORMATION

Citation

Voorrips RE, Maliepaard CA (2012)
The simulation of meiosis in diploid and tetraploid organisms using various genetic models.
BMC Bioinformatics. 2012 Sep 26;13:248.

PedHunter 2.0 – Creation and Verification of Pedigrees within large Genealogies

PedHunter 2.0

:: DESCRIPTION

PedHunter is a software package that facilitates creation and verification of pedigrees within large genealogies.

::DEVELOPER

Richa Agarwala and Woei-jyh (Adam) Lee and Alejandro Schäffer.

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Linux
  • C Compiler

:: DOWNLOAD

 PedHunter

:: MORE INFORMATION

Citation

Agarwala R, Biesecker LG, Hopkins KA, Francomano CA, Schäffer AA
Software for constructing and verifying pedigrees within large Genealogies and an application to the Old Order Amish of Lancaster County.
Genome Research 8:211-221, 1998.

MQscore 1.0 / MQscore_SNP 1.1 – Parametric Linkage analysis of Quantitative Traits in large pedigrees

MQscore 1.0

:: DESCRIPTION

MQscore is a program which can be useful for parametric linkage analysis of quantitative traits on the base of large pedigrees without loops.

MQscore_SNP is a program for multipoint parametric linkage analysis of quantitative traits and SNP markers on the base of large pedigrees without loops.

::DEVELOPER

Laboratory of the Methods of Genetic Analysis , Institute of Cytology and Genetics, Novosibirsk, Russia.

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Linux / Windows / Mac OsX
  • Perl

:: DOWNLOAD

 MQscore , MQscore_SNP

:: MORE INFORMATION

Citation:

Ann Hum Genet. 2010 May;74(3):286-9.
MQScore_SNP software for multipoint parametric linkage analysis of quantitative traits in large pedigrees.
Axenovich TI, Aulchenko YS.

PedPeel 0.0.2 – Prepare Pedigree data for Calculation of Elston-Stewarts’ Likelihood function

PedPeel 0.0.2

:: DESCRIPTION

PedPeel prepares pedigree data for calculation of Elston-Stewarts’ likelihood function. It finds an optimal way to peel a pedigree and returns text file containing 7 description arrays.

::DEVELOPER

Laboratory of the Methods of Genetic Analysis , Institute of Cytology and Genetics, Novosibirsk, Russia.

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Linux / Windows / Mac OsX
  • Perl

:: DOWNLOAD

 PedPeel

:: MORE INFORMATION

Citation:

Comput Biol Chem. 2007 Jun;31(3):173-7. Epub 2007 Mar 24.
Optimal peeling order for pedigrees with incomplete genotypic information.
Belonogova NM, Axenovich TI.