CONSAN 1.2 – Pairwise Structural RNA Alignment

CONSAN 1.2

:: DESCRIPTION

CONSAN is a software of pairwise RNA structural alignment, both unconstrained and constrained on alignment pins.

::DEVELOPER

Robin Dowell, Eddy lab

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Linux

:: DOWNLOAD

 CONSAN

:: MORE INFORMATION

Citation

Dowell, RD and Eddy, SR.
Efficient pairwise RNA structure prediction and alignment using sequence alignment constraints.
BMC Bioinformatics 2006, 7:400 .

FastPairMI – Fast Calculation of Pairwise Mutual Information Based on Kernel Estimation

FastPairMI

:: DESCRIPTION

FastPairMI is a new software implementation for more efficiently computing the mutual information for all pairs of genes from gene expression microarrays.

::DEVELOPER

Peng Qiu

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Windows
  • MatLab

:: DOWNLOAD

FastPairMI

:: MORE INFORMATION

Citation

Qiu P, Gentles AJ, Plevritis SK.
Fast calculation of pairwise mutual information for gene regulatory network reconstruction.
Comput Methods Programs Biomed. 2009 May;94(2):177-80. doi: 10.1016/j.cmpb.2008.11.003. Epub 2009 Jan 22. PMID: 19167129.

CubeX – Calculation of Pairwise Linkage Disequilibrium using Exact Solution

CubeX

:: DESCRIPTION

CubeX calculates haplotype frequencies using the exact solution to the cubic equation rather than an iterative approach.

::DEVELOPER

Tom Gaunt’s group in the MRC IEU

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Linux /Mac OsX / Windows
  • Python

:: DOWNLOAD

 CubeX

:: MORE INFORMATION

Citation:

Gaunt TR, Rodríguez S, Day IN.
Cubic exact solutions for the estimation of pairwise haplotype frequencies: implications for linkage disequilibrium analyses and a web tool ‘CubeX’.
BMC Bioinformatics. 2007 Nov 2;8:428.

GapsMis 0.0.0 / GapMis 0.0.7 / GapMis-OMP 0.0.2 / libgapmis 0.0.9 – Pairwise Short-read Alignment

GapsMis 0.0.0 / GapMis 0.0.7 / GapMis-OMP 0.0.2 / libgapmis 0.0.9

:: DESCRIPTION

GapsMis is a tool for pairwise sequence alignment with a bounded number of gaps.

GapMis is a tool for pairwise sequence alignment with a single gap.

GapMis-OMP is the OpenMP-based version of GapMis.

libgapmis is an ultrafast library for pairwise short-read alignment, based on GapMis, including accelerated SSE-based and GPU-based versions.

::DEVELOPER

the Exelixis Lab

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Linux
  • EMBOSS
  • Python
  • C Compiler

:: DOWNLOAD

 GapsMisGapMis , GapMis-OMP , libgapmis 

:: MORE INFORMATION

Citation

BMC Bioinformatics. 2013;14 Suppl 11:S4. doi: 10.1186/1471-2105-14-S11-S4. Epub 2013 Nov 4.
libgapmis: extending short-read alignments.
Alachiotis N, Berger S, Flouri T, Pissis SP, Stamatakis A.

GapMis: a tool for pairwise sequence alignment with a single gap.
Flouri T, Frousios K, Iliopoulos CS, Park K, Pissis SP, Tischler G.
Recent Pat DNA Gene Seq. 2013 Aug;7(2):84-95.

Tomas Flouri, Kimon Frousios, Costas S. Iliopoulos, Kunsoo Park, Solon P. Pissis, and German Tischler.
Approximate string-matching with a single gap for sequence alignment.
In Proceedings of the Second ACM International Conference on Bioinformatics and Computational Biology (ACM-BCB 2011), pp. 490-492, 2011. ACM Digital Library

NW 3.12 – Pairwise Needleman and Wunsch Sequence Alignment program

NW 3.12

:: DESCRIPTION

NW is an implementation of the Needleman and Wunsch dynamic programming sequence alignment algorithm. It reads PIR format sequence files and reports sequence similarity calculated in a number of different ways. Optionally it can generate a PIR format alignment file.

::DEVELOPER

Andrew C.R. Martin’s Bioinformatics Group at UCL

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Linux

:: DOWNLOAD

 NW

:: MORE INFORMATION

YAP – Pairwise Sequence Alignment Using Secondary Structures

YAP

:: DESCRIPTION

YAP (Yet Another Alignment Program) have the possibility of aligning two sequences of amino acids taking into account different properties, namely secondary structures, transmembranicity etc.

::DEVELOPER

Piero Fariselli

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Linux
  • C Compiler

:: DOWNLOAD

 YAP

:: MORE INFORMATION

SNPduo 1.02a – Pairwise Comparisons of SNP data sets

SNPduo 1.02a

:: DESCRIPTION

SNPduo is designed to provide an analysis of Single Nucleotide Polymorphism (SNP) data between any two individuals. It has been designed based on data exported from Affymetrix CNAT 4.0 or Illumina Beadstudio, as well as data downloaded from the HapMap project. However, provided that the data is formatted correctly SNPduoWeb can analyze any SNP data.

::DEVELOPER

the Pevsner Lab

:: SCREENSHOTS

N/A

:: REQUIREMENTS

:: DOWNLOAD

 SNPduo

:: MORE INFORMATION

Citation

PLoS One. 2009 Aug 21;4(8):e6711. doi: 10.1371/journal.pone.0006711.
Visualization of shared genomic regions and meiotic recombination in high-density SNP data.
Roberson ED, Pevsner J.

LnLCorr – Detect Pairwise Coevolutionary among Residues in a set of Proteins

LnLCorr

:: DESCRIPTION

The LnLCorr package is designed to detect pairwise coevolutionary among residues in a set of proteins using likelihood ratio tests.

::DEVELOPER

Pollock Laboratory

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Linux

:: DOWNLOAD

   LnLCorr

:: MORE INFORMATION

Citation

Wang ZO, Pollock DD:
Coevolutionary patterns in cytochrome coxidase subunit I depend on structural and functional context.
J Mol Evol 2007, 65(5):485-495

GS-Aligner 1.0 – Large-scale Pairwise Sequence Alignment

GS-Aligner 1.0

:: DESCRIPTION

GS-Aligner that uses bit-level operations was developed for aligning genomic sequences. GS-Aligner is efficient in terms of both time and space for aligning two very long genomic sequences and for identifying genomic rearrangements such as translocations and inversions. It is suitable for aligning fairly divergent sequences such as human and mouse genomic sequences. It consists of several efficient components: bit-level coding, search for matching segments between the two sequences as alignment anchors, longest increasing subsequence (LIS), and optimal local alignment. Efforts have been made to reduce the execution time of the program to make it truly practical for aligning very long sequences. Empirical tests suggest that for relatively divergent sequences such as sequences from different mammalian orders or from a mammal and a nonmammalian vertebrate GS-Aligner performs better than existing methods.

::DEVELOPER

Chun-Chieh Shih  and Wen-Hsiung Li

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Linux

:: DOWNLOAD

 GS-Aligner

:: MORE INFORMATION

Citation:

GS-Aligner: A Novel Tool for Aligning Genomic Sequences Using Bit-Level Operations
Chun-Chieh Shih and Wen-Hsiung Li
Mol Biol Evol (2003) 20 (8): 1299-1309.

PALS 1.0 – Pairwise Alignment of Long Sequences

PALS 1.0

:: DESCRIPTION

PALS (Pairwise Aligner for Long Sequences)is public domain software that finds local alignments of long DNA sequences.

::DEVELOPER

Robert Edgar

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Linux / Mac OsX

:: DOWNLOAD

PALS

:: MORE INFORMATION

Citation

R.C. Edgar and E.W. Myers
PILER: identification and classification of genomic repeats.
Bioinformatics. 2005 Jun 1;21 Suppl 1:i152-i158