PESCADOR – Extract and Analyse a Network of Gene and Protein Interactions from a set of Medline abstracts

PESCADOR

:: DESCRIPTION

PESCADOR (Platform for Exploration of Significant Concepts AssociateD to co-Occurrences Relationships) is a web tool that extracts a network of interactions from a set of PubMed abstracts given by a user, and allows filtering the interaction network according to user-defined concepts.

::DEVELOPER

Computational Biology and Data Mining (CBDM) Group

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Web Server

:: DOWNLOAD

 NO

:: MORE INFORMATION

Citation

BMC Bioinformatics. 2011 Nov 9;12:435. doi: 10.1186/1471-2105-12-435.
PESCADOR, a web-based tool to assist text-mining of biointeractions extracted from PubMed queries.
Barbosa-Silva A1, Fontaine JF, Donnard ER, Stussi F, Ortega JM, Andrade-Navarro MA.

HIPPIE 2.2 – study and filter the Network of Human Protein-protein Interaction data

HIPPIE 2.2

:: DESCRIPTION

HIPPIE (Human Integrated Protein-Protein Interaction rEference) is a human PPI dataset with a normalized scoring scheme that integrates multiple experimental PPI datasets.

::DEVELOPER

Computational Biology and Data Mining (CBDM) Group

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Windows/Linux/MacOsX
  • Java

:: DOWNLOAD

 HIPPIE

:: MORE INFORMATION

Citation

HIPPIE v2.0: enhancing meaningfulness and reliability of protein-protein interaction networks.
Alanis-Lobato G, Andrade-Navarro MA, Schaefer MH.
Nucleic Acids Res. 2017 Jan 4;45(D1):D408-D414. doi: 10.1093/nar/gkw985

PLoS One. 2012;7(2):e31826. doi: 10.1371/journal.pone.0031826. Epub 2012 Feb 14.
HIPPIE: Integrating protein interaction networks with experiment based quality scores.
Schaefer MH1, Fontaine JF, Vinayagam A, Porras P, Wanker EE, Andrade-Navarro MA.

NetPathMiner 1.22.0 – R package for Network Path Mining through Gene Expression

NetPathMiner 1.22.0

:: DESCRIPTION

NetPathMiner implements a flexible module-based process flow for network path mining and visualization, which can be fully inte-grated with user-customized functions. It supports construction of various types of genome scale networks from three different pathway file formats, enabling its utility to most common pathway databases. In addition, NetPathMiner provides different visualization techniques to facilitate the analysis of even thousands of output paths.

::DEVELOPER

NetPathMiner team

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Windows/ Linux/MacOsX
  • R
  • BioConductor

:: DOWNLOAD

 NetPathMiner 

:: MORE INFORMATION

Citation

NetPathMiner: R/Bioconductor package for network path mining through gene expression.
Mohamed A, Hancock T, Nguyen CH, Mamitsuka H.
Bioinformatics. 2014 Jul 28. pii: btu501.

NetSeed – Identify the Seed sets of Networks

NetSeed

:: DESCRIPTION

NetSeed is a software package for identifying the seed sets of networks

::DEVELOPER

the Borenstein Lab

:: SCREENSHOTS

N/A

:: REQUIREMENTS

:: DOWNLOAD

 NetSeed

:: MORE INFORMATION

Citation

Rogan Carr and Elhanan Borenstein (2012)
NetSeed: A network-based reverse-ecology tool for calculating the metabolic interface of an organism with its environment.
Bioinformatics. doi: 10.1093/bioinformatics/btr721.

lpNet 2.18.0 – Linear Programming Model for Network Inference

lpNet 2.18.0

:: DESCRIPTION

lpNet aims at infering biological networks, in particular signaling and gene networks.

::DEVELOPER

Lars Kaderali

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Linux / Windows/ MacOsX
  • R
  • BioConductor

:: DOWNLOAD

 lpNet

:: MORE INFORMATION

Citation

lpNet: a linear programming approach to reconstruct signal transduction networks.
Matos MR, Knapp B, Kaderali L.
Bioinformatics. 2015 May 29. pii: btv327

WordCloud 3.1.3 – Cytoscape plugin to Generate a Visual Summary of a Network

WordCloud 3.1.3

:: DESCRIPTION

The WordCloud plugin is a Cytoscape plugin that generates a visual summary of a network. It displays string attributes associated with nodes in the network as a tag cloud, where more frequent words are displayed using a larger font size. Word co-occurence in a phrase can be visualized by arranging words in clusters or as a network.

::DEVELOPER

Bader Lab

:: SCREENSHOTS

:: REQUIREMENTS

:: DOWNLOAD

 WordCloud

:: MORE INFORMATION

Citation

Source Code Biol Med. 2011 Apr 7;6:7.
WordCloud: a Cytoscape plugin to create a visual semantic summary of networks.
Oesper L, Merico D, Isserlin R, Bader GD.

MCODE 1.5.1 – Cytoscape plugin that finds Clusters in a Network

MCODE 1.5.1

:: DESCRIPTION

MCODE is a Cytoscape plugin that finds clusters (highly interconnected regions) in a network. Clusters mean different things in different types of networks. For instance, clusters in a protein-protein interaction network are often protein complexes and parts of pathways, while clusters in a protein similarity network represent protein families.

::DEVELOPER

Bader Lab

:: SCREENSHOTS

:: REQUIREMENTS

:: DOWNLOAD

 MCODE

:: MORE INFORMATION

Citation

Bader GD, Hogue CW.
An automated method for finding molecular complexes in large protein interaction networks.
BMC Bioinformatics. 2003 Jan 13;4(1):2.

linkcomm 1.0-11 – Tools for Generating, Visualizing, and Analysing Link Communities in Networks

linkcomm 1.0-11

:: DESCRIPTION

linkcomm is an R package for the generation, visualization, and analysis of link communities in networks of arbitrary size and type.

::DEVELOPER

linkcomm team

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Windows / Linux / MacOSX
  • R

:: DOWNLOAD

  linkcomm

:: MORE INFORMATION

Citation

Bioinformatics. 2011 Jul 15;27(14):2011-2. doi: 10.1093/bioinformatics/btr311. Epub 2011 May 19.
linkcomm: an R package for the generation, visualization, and analysis of link communities in networks of arbitrary size and type.
Kalinka AT, Tomancak P.

HAC 1.2.1 – Hierarchical Agglomerative Clustering for a large-scale Network data

HAC 1.2.1

:: DESCRIPTION

HAC is developed for fast clustering of heterogeneous interaction networks.

::DEVELOPER

Joel Bader lab

:: SCREENSHOTS

N/A

::REQUIREMENTS

  • Linux

:: DOWNLOAD

 HAC

:: MORE INFORMATION

Citation

BMC Bioinformatics. 2011 Feb 15;12 Suppl 1:S44. doi: 10.1186/1471-2105-12-S1-S44.
Resolving the structure of interactomes with hierarchical agglomerative clustering.
Park Y, Bader JS.

NeEMO 1.0 – NEtwork Enthalpic MOdelling

NeEMO 1.0

:: DESCRIPTION

NeEMO is a tool for the evaluation of stability changes using an effective representation of proteins based on residue interaction networks (RINs).

::DEVELOPER

The BioComputing UP lab

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Web Browser

:: DOWNLOAD

 NO

:: MORE INFORMATION

Citation:

BMC Genomics. 2014;15 Suppl 4:S7. doi: 10.1186/1471-2164-15-S4-S7. Epub 2014 May 20.
NeEMO: a method using residue interaction networks to improve prediction of protein stability upon mutation.
Giollo M, Martin AJ, Walsh I, Ferrari C, Tosatto SC.