PWKmeans 1.0 – Penalize & weight K-means Extends the Target Function of K-means

PWKmeans 1.0

:: DESCRIPTION

PWKmeans penalized and weighted K-means extends the target function of K-means.

::DEVELOPER

George C. Tseng 

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Linux
  • C Compiler

:: DOWNLOAD

 PWKmeans

:: MORE INFORMATION

Citation

George C. Tseng. (2007).
Penalized and weighted K-means for clustering with scattered objects and prior information in high-throughput biological data.
Bioinformatics. 23:2247-2255.

SeSAW 2.0 – Functional Mapping by Sequence-Derived Structural Alignment Weights

SeSAW 2.0

:: DESCRIPTION

SeSAW (sequence-derived structural alignment weights) is a web-based program for identifying functionally or evolutionarily conserved motifs in protein structures by locating sequence and structural similarities, and quantifying these at the level of individual residues. Results can be visualized in 2D, as annotated alignments, or in 3D, as structural superpositions. An example is given for both an experimentally determined query structure and a homology model.

::DEVELOPER

Department of Genome Informatics; Research Institute for Microbial Diseases; Osaka University

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Web Browser

:: DOWNLOAD

  NO

:: MORE INFORMATION

Citation

SeSAW: balancing sequence and structural information in protein functional mapping.
Standley DM, Yamashita R, Kinjo AR, Toh H, Nakamura H.
Bioinformatics. 2010 May 1;26(9):1258-9. Epub 2010 Mar 17.

Weighbor 1.2 – Weighted Neighbor Joining

Weighbor 1.2

:: DESCRIPTION

Weighbor is a fast, accurate, and essentially un-biased alternative method for constructing evolutionary trees from a sequence-derived distance matrix.

::DEVELOPER

William J. Bruno, Nicholas D. Socci, and Aaron L. Halpern.

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Linux

:: DOWNLOAD

 Weighbor

:: MORE INFORMATION

Citation:

William J. Bruno, Nicholas D. Socci, and Aaron L. Halpern
Weighted Neighbor Joining: A Likelihood-Based Approach to Distance-Based Phylogeny Reconstruction,
Mol. Biol. Evol. 17 (1): 189-197 (2000)