PSpro 2.0 – Predict Secondary Structure, Solvent Accessibility, and Residue-residue Contacts

PSpro 2.0

:: DESCRIPTION

PSpro is a software to predict secondary structure, solvent accessibility, and residue-residue contacts . It is essentially a bundle of three tools including SSpro 4.1, ACCpro 4.1 and NNcon 1.0.

::DEVELOPER

Dr. Jianlin Cheng

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Linux

:: DOWNLOAD

 PSpro 

:: MORE INFORMATION

RNAMute / XRNAmute – RNA Secondary Structure Mutation Analysis Tool

RNAMute / XRNAmute

:: DESCRIPTION

RNAmute is an application that provides a user friendly interface for analyzing the effects of point mutations on RNAs secondary structure.

XRNAmute is RNAmute web server for the mutational analysis of RNA secondary structures.

::DEVELOPER

A.Churkin and D. Barash (dbarash@cs.bgu.ac.il)

:: SCREENSHOTS

:: REQUIREMENTS

  • Linux / Mac / Windows
  • Java

:: DOWNLOAD

 RNAMute

:: MORE INFORMATION

Citation

Nucleic Acids Res. 2011 Jul;39(Web Server issue):W92-9. doi: 10.1093/nar/gkr207. Epub 2011 Apr 7.
The RNAmute web server for the mutational analysis of RNA secondary structures.
Churkin A1, Gabdank I, Barash D.

A.Churkin and D. Barash,
RNAMute: RNA Secondary Structure Mutation Analysis Tool,”
BMC Bioinformatics, 7:221, 2006.

SIMPA 96 – Predict Secondary Structure of Proteins

SIMPA 96

:: DESCRIPTION

SIMPA (SIMilar Peptide Analysis) is a program for predicting the secondary structure of proteins. 3 states are taken into consideration: alpha helix (H), beta strand (b) and aperiodical structures (C). This program is based on the nearest neighbour notion. It provides a Q3 result of 67%

::DEVELOPER

Jonathan Levin  jon@glycine.jouy.inra.fr

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Linux

:: DOWNLOAD

SIMPA

:: MORE INFORMATION

Citation

Levin JM, Pascarella S, Argos P, Garnier J.
Quantification of secondary structure prediction improvement using multiple alignments. (1993)
Protein Eng. 6:849-54.

RNAentropy 1.0 – Compute RNA Secondary Structure Conformational Entropy

RNAentropy 1.0

:: DESCRIPTION

RNAentropy implements two cubic time algorithms to compute the RNA thermodynamic structural entropy.

::DEVELOPER

Clote Lab 

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Linux

:: DOWNLOAD

 RNAentropy

:: MORE INFORMATION

Citation

RNA Thermodynamic Structural Entropy.
Garcia-Martin JA, Clote P.
PLoS One. 2015 Nov 10;10(11):e0137859. doi: 10.1371/journal.pone.0137859.

VARNA 3-93 – Java pplet for Drawing the Secondary Structure of RNA

VARNA 3-93

:: DESCRIPTION

VARNA (Viral Associated RNAs) is Java lightweight Applet dedicated to drawing the secondary structure of RNA. It is also a Swing component that can be very easily included in an existing Java code working with RNA secondary structure to provide a fast and interactive visualization.Being free of fancy external library dependency and/or network access, the VARNA Applet can be used as a base for a standalone applet. It looks reasonably good and scales up or down nicely to adapt to the space available on a web page, thanks to the anti-aliasing drawing primitives of Swing.

::DEVELOPER

Created by: Kevin Darty,  Alain Denise and Yann Ponty ( ponty@lri.fr)

:: SCREENSHOTS

:: REQUIREMENTS

  • Windows / MacOsX / Linux
  • Java

:: DOWNLOAD

VARNA

:: MORE INFORMATION

Citation

VARNA: Interactive drawing and editing of the RNA secondary structure
Kévin Darty, Alain Denise and Yann Ponty
Bioinformatics, pp. 1974-1975, Vol. 25, no. 15, 2009

RNABOB 2.2 – Fast Pattern Searching for RNA Secondary Structures

RNABOB 2.2

:: DESCRIPTION

RNABOB is an implementation of D. Gautheret’s RNAMOT, but with a different underlying algorithm using a nondeterministic finite state machine with node rewriting rules. (Computer scientists would probably cringe in horror. It works, and it’s fast, but is it street legal in a computer science department? Who knows.) An RNABOB motif is a consensus pattern a la PROSITE patterns, but with base-pairing.

::DEVELOPER

Sean Eddy, Eddy lab

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Linux
  • C Compiler

:: DOWNLOAD

  RNABOB

:: MORE INFORMATION

NIAS-Server 1.0 – Neighbors Influence of Amino acids and Secondary Structures in Proteins

NIAS-Server 1.0

:: DESCRIPTION

NIAS is a server to help the analysis of the conformational preferences of amino acid residues in proteins.

::DEVELOPER

SBCB – Structural Bioinformatics and Computational Biology Lab

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Web browser

:: DOWNLOAD

 NO

:: MORE INFORMATION

Citation:

Borguesan, B.; Inostroza-Ponta, M.; Dorn, M.
NIAS-Server: Neighbors Influence of Amino acids and Secondary Structures in Proteins.
Journal of Computational Biology. March 2017, 24(3): 255-265.

forna 20150415 – RNA Secondary Structure Visualization Using a Force Directed Graph Layout

forna 20150415

:: DESCRIPTION

forna is a web-based tool for displaying RNA secondary structure which allows users to easily convert sequences and secondary structures to clean, concise and customizable visualizations.

::DEVELOPER

Peter Kerpedjiev

:: SCREENSHOTS

forna

:: REQUIREMENTS

  • Windows/ Linux/ MacOsX
  • Python

:: DOWNLOAD

 forna

:: MORE INFORMATION

Citation:

forna (force-directed RNA): Simple and Effective Online RNA Secondary Structure Diagrams.
Kerpedjiev P, Hammer S, Hofacker IL.
Bioinformatics. 2015 Jun 22. pii: btv372.

RME 1.1 – RNA Secondary Structure Prediction incorporating Experimental Constraints

RME 1.1

:: DESCRIPTION

RME predict RNA secondary structure by integrating the free energy model with probing data (SHAPE, PARS, DMS).

::DEVELOPER

Lu Lab, School of Life Sciences, Tsinghua University, China

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Linux

:: DOWNLOAD

 RME

:: MORE INFORMATION

Citation

Nucleic Acids Res. 2015 Sep 3;43(15):7247-59. doi: 10.1093/nar/gkv706. Epub 2015 Jul 13.
Improved prediction of RNA secondary structure by integrating the free energy model with restraints derived from experimental probing data.
Wu Y, Shi B, Ding X, Liu T, Hu X, Yip KY, Yang ZR, Mathews DH, Lu ZJ

RNAex – RNA Secondary Structure Prediction Server

RNAex

:: DESCRIPTION

RNAex is an RNA secondary structure prediction enhanced by high-throughput experimental data

::DEVELOPER

Lu Lab, School of Life Sciences, Tsinghua University, China

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Web browser

:: DOWNLOAD

 NO

:: MORE INFORMATION

Citation

RNAex: an RNA secondary structure prediction server enhanced by high-throughput structure-probing data.
Wu Y, Qu R, Huang Y, Shi B, Liu M, Li Y, Lu ZJ.
Nucleic Acids Res. 2016 May 2. pii: gkw362.