Tag: SAD

SAD – Salmon Anomaly Detection

SAD

:: DESCRIPTION

SAD detects the potential misquantifications for the RNA-seq transcript expression estimation made by Salmon. SAD detects large deviation of the observed coverage distribution from the expected coverage distribution for each transcript, and use the deviation as an indicator of misquantifications.

::DEVELOPER

Kingsford Group

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Linux / MacOs

:: DOWNLOAD

SAD

:: MORE INFORMATION

Citation

Cong Ma, Carl Kingsford (2019).
Detecting, categorizing, and correcting coverage anomalies of RNA-seq quantification.
Cell Systems, in press..

SOLVE / RESOLVE 2.13 – Automated Crystallographic Structure Solution for MIR, SAD, and MAD

SOLVE / RESOLVE 2.13

:: DESCRIPTION

SOLVE is a program that can carry out all the steps of macromolecular structure determination from scaling data to calculation of an electron density map, automatically.

RESOLVE is a program that improves electron density maps.

::DEVELOPER

Thomas C. Terwilliger

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  •  Linux / Mac OsX

:: DOWNLOAD

 SOLVE / RESOLVE

:: MORE INFORMATION

Citation

SOLVE:
Terwilliger, T.C. and J. Berendzen. (1999)
“Automated MAD and MIR structure solution”.
Acta Crystallographica D55, 849-861.

RESOLVE:
Terwilliger, T. C. (2000)
“Maximum likelihood density modification,”
Acta Cryst. D56, 965-972.

Terwilliger, T. C. (2003)
“Automated main-chain model building by template matching and iterative fragment extension”
Acta Cryst. D59, 38-44.