RAT – A software for Rapid Association Tests

RAT

:: DESCRIPTION

RAT (Rapid Association Test) is a software for testing association between single nucleotide polymorphisms (SNPs) and a disease. The main advantage of RAT is its ability to calculate accurately and quickly high significance disease association. For large data set and low p-values, RAT is 2-4 orders of magnitude faster than the standard permutation test.

::DEVELOPER

Ron Shamir’s lab

:: SCREENSHOTS

N/A

::REQUIREMENTS

Windows with Cygwin /Linux

:: DOWNLOAD

RAT

:: MORE INFORMATION

Citation

Gad Kimmel and Ron Shamir.
A Fast Method for Computing High Significance Disease Association in Large Population-Based Studies.
Am. J. Hum. Genet. 2006

Virtual Twitch 2.2.1 – Simulation of the Rat Phrenic Nerve-hemidiaphragm Preparation

Virtual Twitch 2.2.1

:: DESCRIPTION

The Virtual Twitch is a simulation of the rat phrenic nerve-hemidiaphragm preparation, used to the study the actions of neuromuscular blocking and reversal agents, and other drugs which affect neuromuscular transmission. The hemidiaphraghm is a large, focally innervated, respiratory skeletal muscle, composed of fast-type muscle fibres. Electrical stimulation of the phrenic nerve evokes fast, shorting-lasting muscle twitches.

::DEVELOPER

the Strathclyde Institute of Pharmacy and Biomedical Sciences

:: SCREENSHOTS

:: REQUIREMENTS

Windows

:: DOWNLOAD

Virtual Twitch

:: MORE INFORMATION

RAT 1.0 – Recombination Analysis Tool for High Throughput Analysis of Genomic Sequence

RAT 1.0

:: DESCRIPTION

RAT (Recombination Analysis Tool)is an uncomplicated and intuitive cross-platform Java-based application intended for high-throughput, distance-based analysis of both DNA and protein multiple sequence alignments, in any one of seven different file formats. All of RAT’s operations are carried out through GUI’s, and all output can be saved as data files (.txt, .xls, .csv), or .jpg files in the case of graphical outputs. RAT is intuitive and easy to use, and only requires a minimum of input from the user. All the parameters have default values, all of which may be changed by the user.

::DEVELOPER

DICKS COMPUTATIONAL BIOLOGY GROUP

:: SCREENSHOTS

:: REQUIREMENTS

Windows/ Linux / Mac OsX
JAVA

:: DOWNLOAD

RAT

:: MORE INFORMATION

Citation:

Etherington GJ, Dicks J and Roberts IN (2005)
Recombination Analysis Tool (RAT): a program for the high-throughput detection of recombination.
Bioinformatics 21(3):278-281.