MetalionRNA – Metal Ion Binding Site Predictor

MetalionRNA

:: DESCRIPTION

MetalionRNA is a novel bioinformatic method for predicting metal-binding sites in RNA structures.

::DEVELOPER

Bujnicki lab

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Web browser

:: DOWNLOAD

 NO

:: MORE INFORMATION

Citation

Computational methods for prediction of RNA interactions with metal ions and small organic ligands.
Philips A, Łach G, Bujnicki JM.
Methods Enzymol. 2015;553:261-85. doi: 10.1016/bs.mie.2014.10.057.

MetaSSPred – Balanced Secondary Structure Predictor

MetaSSPred

:: DESCRIPTION

MetaSSPred is a well-balanced Secondary Structure predictor

::DEVELOPER

Hoque’s Lab, University of New Orleans

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Linux

:: DOWNLOAD

 MetaSSPred

:: MORE INFORMATION

Citation

J Theor Biol. 2015 Nov 5;389:60-71. doi: 10.1016/j.jtbi.2015.10.015. [Epub ahead of print]
A balanced secondary structure predictor.
Nasrul Islam M, Iqbal S, Katebi AR, Tamjidul Hoque M

Dragon PolyA Spotter 1.200 – Predictor of poly(A) motifs within Human Genomic DNA sequences

Dragon PolyA Spotter 1.200

:: DESCRIPTION

The Dragon PolyA Spotter is a tool to predict polyadenylation signals variants in primary human genomic sequences. The application displays predicted polyA signal variants and their positions in each submitted fasta sequence.

::DEVELOPER

Dragon PolyA Spotter Team @ Computational Bioscience Research Center ,  King Abdullah University of Science and Technology

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Linux / Windows/ MacOsX
  • C++ Compiler

:: DOWNLOAD

 Dragon PolyA Spotter

:: MORE INFORMATION

Citation

Bioinformatics. 2012 Jan 1;28(1):127-9. Epub 2011 Nov 15.
Dragon PolyA Spotter: predictor of poly(A) motifs within human genomic DNA sequences.
Kalkatawi M, Rangkuti F, Schramm M, Jankovic BR, Kamau A, Chowdhary R, Archer JA, Bajic VB.

SPEPLip – Predictor of Signal Peptide and Lipoprotein Cleavage Sites in Proteins

SPEPLip

:: DESCRIPTION

SPEPlip is a neural network-based method, trained and tested on a set of experimentally derived signal peptides from eukaryotes and prokaryotes. SPEPlip identifies the presence of sorting signals and predicts their cleavage sites.

::DEVELOPER

Bologna Biocomputing Group

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Windows/Linux/MacOsX
  • Perl
  • C Compiler

:: DOWNLOAD

 SPEPLip

:: MORE INFORMATION

Citation

Bioinformatics. 2003 Dec 12;19(18):2498-9.
SPEPlip: the detection of signal peptide and lipoprotein cleavage sites.
Fariselli P, Finocchiaro G, Casadio R.

CCHMMPROF – Predictor of Coiled-Coils Regions in Proteins Exploiting Evolutionary Information

CCHMMPROF

:: DESCRIPTION

CCHMM_PROF is a hidden Markov model that exploits the information contained in multiple sequence alignments (profiles) to predict coiled-coil regions. The new method discriminates coiled-coil sequences with an accuracy of 97% and achieves a true positive rate of 79% with only 1% of false positives. Furthermore, when predicting the location of coiled-coil segments in protein sequences, the method reaches an accuracy of 80% at the residue level and a best per-segment and per-protein efficiency of 81% and 80%, respectively. The results indicate that CCHMM_PROF outperforms all the existing tools and can be adopted for large-scale genome annotation.

::DEVELOPER

Bologna Biocomputing Group

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Windows/Linux/MacOsX
  • Python

:: DOWNLOAD

 CCHMMPROF

:: MORE INFORMATION

Citation

Bioinformatics. 2009 Nov 1;25(21):2757-63. Epub 2009 Sep 10.
CCHMM_PROF: a HMM-based coiled-coil predictor with evolutionary information.
Bartoli L, Fariselli P, Krogh A, Casadio R.

PS-COILS 1.0 – Coiled-coil Predictor

PS-COILS 1.0

:: DESCRIPTION

PSCOILS is a simple evolution of COILS and PCOILS  programs. It uses the same parameters that were developed for COILS and exploits both sequence and evolutionary information (in the form of sequence profiles).

::DEVELOPER

Piero Fariselli

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Linux/ MacOsX / WIndows
  • Python

:: DOWNLOAD

 PS-COILS 

:: MORE INFORMATION

Protein Prowler 1.2 – Subcellular Localisation Predictor

Protein Prowler 1.2

:: DESCRIPTION

The PProwler (Protein Prowler) Subcellular Localisation Predictor accepts amino acid sequences, presented in the FASTA format, and determines the localisation of the protein.

::DEVELOPER

Bioinformatics group,The University of Queensland

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Web Browser

:: DOWNLOAD

  NO

:: MORE INFORMATION

Citation

Bioinformatics. 2005 May 15;21(10):2279-86. Epub 2005 Mar 3.
Prediction of subcellular localization using sequence-biased recurrent networks.
Bodén M, Hawkins J.

BOMP – The beta-barrel Outer Membrane Protein Predictor

BOMP

:: DESCRIPTION

BOMP is a tool for prediction of beta-barrel integral outer membrane proteins (BOMPs). The user may submit a list of proteins, and receive a list of predicted BOMPs.

::DEVELOPER

Uni Computing

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Web Browser

:: DOWNLOAD

 NO

:: MORE INFORMATION

Citation

Berven FS, Flikka K, Jensen HB, Eidhammer I.
BOMP: a program to predict integral beta-barrel outer membrane proteins encoded within genomes of Gram-negative bacteria .
Nucleic Acids Res. 2004 Jul 1;32(Web Server issue):W394-9

CalPred 1.0 – Calcium Binding Protein Predictor

CalPred 1.0

:: DESCRIPTION

CalPred is a “tool for EF-hand calcium binding protein prediction and calcium binding region identification” using machine learning techniques.

::DEVELOPER

Dr. Pradeep K. Naik 

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Windows

:: DOWNLOAD

 CalPred

:: MORE INFORMATION

SNPs&GO – Predictor of Human Disease-related Mutations in Proteins with Functional Annotations

SNPs&GO

:: DESCRIPTION

 SNPs&GO is a server for the prediction of single point protein mutations likely to be involved in the insurgence of diseases in humans.

::DEVELOPER

Bologna Biocomputing Group

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Web Browser

:: DOWNLOAD

 No. Only Web Service

:: MORE INFORMATION

Citation

Calabrese R, Capriotti E, Fariselli P, Martelli PL, Casadio R
Functional annotations improve the predictive score of human disease-related mutations in proteins
Hum Mutat 30:1237-1244 (2009)