PredGPI – Predictor of GPI-Anchored Proteins

PredGPI

:: DESCRIPTION

PredGPI is a prediction system for GPI-anchored proteins. It is based on a support vector machine (SVM) for the discrimination of the anchoring signal, and on a Hidden Markov Model (HMM) for the prediction of the most probable omega-site

::DEVELOPER

Bologna Biocomputing Group

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Web Browser

:: DOWNLOAD

 No. Only Web Service

:: MORE INFORMATION

Citation

Pierleoni A, Martelli PL, Casadio R
PredGPI: a GPI anchor predictor
BMC Bioinformatics- 9:392 (2008)

MemLoci – Subcellular Localization Predictor for Membrane Proteins

MemLoci

:: DESCRIPTION

 MemLoci is a predictor for the subcellular localization of proteins associated or inserted in eukaryotes membranes.

::DEVELOPER

Bologna Biocomputing Group

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Web Browser

:: DOWNLOAD

 No. Only Web Service

:: MORE INFORMATION

Citation

MemLoci: predicting subcellular localization of membrane proteins in eukaryotes.
Pierleoni A, Martelli PL, Casadio R.
Bioinformatics. 2011 May 1;27(9):1224-30. Epub 2011 Mar 2.

DCON – Predictor of Disulfide Connectivity in Proteins

DCON

:: DESCRIPTION

 DCON is a predictor of disulfide connectivity in proteins

::DEVELOPER

Bologna Biocomputing Group

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Linux

:: DOWNLOAD

 DCON

:: MORE INFORMATION

Citation

Prediction of disulfide connectivity in proteins
Piero Fariselli and Rita Casadio
Bioinformatics (2001) 17 (10): 957-964.

CORNET – Predictor of Residue Contacts in Proteins

CORNET

:: DESCRIPTION

CORNET is a method based on neural networks for predicting contact maps of proteins using as input chemico-physical and evolutionary information.

::DEVELOPER

Bologna Biocomputing Group

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Web Browser

:: DOWNLOAD

 No, Only Web Service

:: MORE INFORMATION

Citation

Protein Eng. 1999 Jan;12(1):15-21.
A neural network based predictor of residue contacts in proteins.
Fariselli P, Casadio R.

CCHMM – Predictor of Coiled-Coils Regions in Proteins

CCHMM

:: DESCRIPTION

CCHMM (Coiled-Coil Domains with Hidden Markov Models) is a predictor of coiled-coil segments in proteins. The software bases on hidden Markov models that complement the existing methods and outperforms them in the task of locating structurally-defined coiled-coil segments.

::DEVELOPER

Bologna Biocomputing Group

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Web Browser

:: DOWNLOAD

 No, Only Web Service

:: MORE INFORMATION

Citation

Prediction of Structurally-Determined Coiled-Coil Domains with Hidden Markov Models
Piero Fariselli, Daniele Molinini, Rita Casadio and Anders Krogh
Lecture Notes in Computer Science, 2007, Volume 4414, Bioinformatics Research and Development, Pages 292-302

BaCelLo – Predictor for the Subcellular Localization of Proteins in Eukaryotes

BaCelLo

:: DESCRIPTION

BaCelLo (Balanced Subcellular Localization Predictor) is a predictor for the subcellular localization of proteins in eukaryotes. It is based on a decision tree of several support vector machines (SVMs), it classifies up to four localizations for Fungi and Metazoan proteins and five localizations for Plant ones

::DEVELOPER

Bologna Biocomputing Group

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Web Browser

:: DOWNLOAD

 No, Only Web Service

:: MORE INFORMATION

Citation

BaCelLo: a Balanced subCellular Localization predictor.
Andrea Pierleoni 1, Pier Luigi Martelli1, Piero Fariselli1 and Rita Casadio1
Bioinformatics, 22, e408-e416.

PhD-SNP 2.0.6 – Predictor of human Deleterious Single Nucleotide Polymorphisms

PhD-SNP 2.0.6

:: DESCRIPTION

PhD-SNP supports Vector Machine based method to discriminate between neutral or disease-related single point protein mutations.

::DEVELOPER

the Structural Bioinformatics Unit

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Linux / Mac / Windows
  • Python

:: DOWNLOAD

 PhD-SNP

:: MORE INFORMATION

Citation

Bioinformatics. 2006 Nov 15;22(22):2729-34. Epub 2006 Aug 7.
Predicting the insurgence of human genetic diseases associated to single point protein mutations with support vector machines and evolutionary information.
Capriotti E, Calabrese R, Casadio R.

EVIGAN 1.0 – Eukaryotic Gene Predictor

EVIGAN 1.0

:: DESCRIPTION

Evigan is an automated gene annotation program for eukaryotic genomes, employing probabilistic inference to integrate multiple sources of gene evidence. The probabilistic model is a dynamic Bayes network whose parameters are adjusted to maximize the probability of observed evidence. Consensus gene predictions are then derived by maximum likelihood decoding, yielding n-best models (with probabilities for each).

::DEVELOPER

Structured Learning at Penn

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Linux

:: DOWNLOAD

  Evigan

:: MORE INFORMATION

Citation

Evigan: a hidden variable model for integrating gene evidence for eukaryotic gene prediction.
Liu Q, Mackey AJ, Roos DS, Pereira FC.
Bioinformatics. 2008 Mar 1;24(5):597-605. Epub 2008 Jan 10.