PHDcleav – Prediction of Human Dicer Cleavage

PHDcleav

:: DESCRIPTION

PHDcleav is a webserver to predict Dicer cleavage sites in pre-miRNA. Dicer, an RNase III enzyme, plays vital role in RNA interference pathway, processes both pre-miRNAs (precursor microRNAs) and double-stranded (ds) RNAs to generate effector molecules. Thus it is very important to know true Dicer processing sites in the pre-miRNA molecules to understand the RNA interference pathway.

::DEVELOPER

PHDcleav team 

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Web Browser

:: DOWNLOAD

 NO

:: MORE INFORMATION

Citation

BMC Bioinformatics. 2013;14 Suppl 14:S9. doi: 10.1186/1471-2105-14-S14-S9. Epub 2013 Oct 9.
PHDcleav: a SVM based method for predicting human Dicer cleavage sites using sequence and secondary structure of miRNA precursors.
Ahmed F, Kaundal R, Raghava GP.

SPEPLip – Predictor of Signal Peptide and Lipoprotein Cleavage Sites in Proteins

SPEPLip

:: DESCRIPTION

SPEPlip is a neural network-based method, trained and tested on a set of experimentally derived signal peptides from eukaryotes and prokaryotes. SPEPlip identifies the presence of sorting signals and predicts their cleavage sites.

::DEVELOPER

Bologna Biocomputing Group

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Windows/Linux/MacOsX
  • Perl
  • C Compiler

:: DOWNLOAD

 SPEPLip

:: MORE INFORMATION

Citation

Bioinformatics. 2003 Dec 12;19(18):2498-9.
SPEPlip: the detection of signal peptide and lipoprotein cleavage sites.
Fariselli P, Finocchiaro G, Casadio R.