JAMP 1.0 – multivariate GWAS Analysis

JAMP 1.0

:: DESCRIPTION

JAMP (Joint Genetic Association of Multiple Phenotypes) uses raw data as input and evaluates the multivariate evidence for association of multiple phenotypes for a SNP. It also provides a family-wise corrected P-value.

::DEVELOPER

CTG (Complex Traits Genetics) Lab

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Windows / Linux / MacOSX
  • Python
  • PLINK

:: DOWNLOAD

 JAMP

:: MORE INFORMATION

MultiMeta 0.1 – Meta-analysis of Multivariate Genome Wide Association Studies

MultiMeta 0.1

:: DESCRIPTION

The R package MultiMeta provides an implementation of the inverse-variance based method for meta-analysis, generalized to an n-dimensional setting.

::DEVELOPER

Dragana Vuckovic <dragana.vuckovic at burlo.trieste.it>

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Linux / MacOsX / Windows
  • R

:: DOWNLOAD

 MultiMeta

:: MORE INFORMATION

Citation:

MultiMeta: an R package for meta-analyzing multi-phenotype genome-wide association studies.
Vuckovic D, Gasparini P, Soranzo N, Iotchkova V.
Bioinformatics. 2015 Apr 22. pii: btv222

LKM 2.0 / LFKM 2.0 / MFKM 1.1 – Quantitative Traits in Longitudinal ( Multivariate) (Family) Data

LKM 2.0 / LFKM 2.0 / MFKM 1.1

:: DESCRIPTION

LKM / LFKM / MFKM is an R package of gene based kernel machine regression for quantitative traits in longitudinal (Multivariate) (Family) Data.

::DEVELOPER

Qi Yan

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Linux
  • R
:: DOWNLOAD

LKM / LFKM / MFKM

:: MORE INFORMATION

Citation

Yan Q, Weeks DE, Tiwari HK, Yi N, Zhang K, Gao G, Lin WY, Lou XY, Chen W, Liu N.
Rare-Variant Kernel Machine Test for Longitudinal Data from Population and Family Samples.
Hum Hered. 2015;80(3):126-38. doi: 10.1159/000445057. Epub 2016 Apr 29. PMID: 27161037; PMCID: PMC4940283.

Yan Q, Weeks DE, Celedón JC, Tiwari HK, Li B, Wang X, Lin WY, Lou XY, Gao G, Chen W, Liu N.
Associating Multivariate Quantitative Phenotypes with Genetic Variants in Family Samples with a Novel Kernel Machine Regression Method.
Genetics. 2015 Dec;201(4):1329-39. doi: 10.1534/genetics.115.178590. Epub 2015 Oct 19. PMID: 26482791; PMCID: PMC4676518.

jointSeg 0.7.0- Joint segmentation of multivariate (copy number) signals

jointSeg 0.7.0

:: DESCRIPTION

The jointSeg R package implements functions to quickly segment multivariate signals into piecewise constant profiles. A typical application is the joint segmentation of total DNA copy numbers and allelic ratios obtained from Single Nucleotide Polymorphism (SNP) microarrays in cancer studies.

::DEVELOPER

Laboratoire de Mathématiques et Modélisation d’Évry

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Windows/Linux/ MacOsX
  • R package

:: DOWNLOAD

 jointSeg

:: MORE INFORMATION

Citation

Brief Bioinform. 2014 Sep 8. pii: bbu026.
Performance evaluation of DNA copy number segmentation methods.
Pierre-Jean M, Rigaill G, Neuvial P.

Igloo-Plot / Web-igloo – Interactively Visualizing multivariate data without Feature Decomposition

Igloo-Plot / Web-igloo

:: DESCRIPTION

Igloo-Plot is a tool for efficient visualization of multidimensional datasets.

Web-Igloo visualizes multivariate data in a 2D chart of multiple quantitative variables represented as anchors on a semicircle.

::DEVELOPER

Web-igloo team

:: SCREENSHOTS

:: REQUIREMENTS

  • WIndows / Linux

:: DOWNLOAD

Igloo-Plot

:: MORE INFORMATION

Citation

Kuntal BK, Ghosh TS, Mande SS.
Igloo-Plot: a tool for visualization of multidimensional datasets.
Genomics. 2014 Jan;103(1):11-20. doi: 10.1016/j.ygeno.2014.01.004. Epub 2014 Jan 17. PMID: 24444495.

Kuntal BK, Mande SS.
Web-igloo: a web based platform for multivariate data visualization.
Bioinformatics. 2017 Feb 15;33(4):615-617. doi: 10.1093/bioinformatics/btw669. PMID: 27797774.