MDL 1.0 – Minimum Description Length for the detection of Phylogenetics Breakpoints

MDL 1.0

:: DESCRIPTION

 MDL is a software of Minimum Description Length for the detection of phylogenetics breakpoints

::DEVELOPER

Cécile Ané

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Linux/windows/ MacOsX
  • R Package

:: DOWNLOAD

 MDL

:: MORE INFORMATION

Citation

Cécile Ané
Detecting Phylogenetic Breakpoints and Discordance from Genome-Wide Alignments for Species Tree Reconstruction
Genome Biol Evol (2011) 3 246-258.

QuantiSNP 2.3 – Copy Number Variation (CNV) Detection

QuantiSNP 2.3

:: DESCRIPTION

QuantiSNP is an analytical tool for the analysis of copy number variation using whole genome SNP genotyping data. In its first implementation it was developed for data arising from Illumina® platforms

::DEVELOPER

QuantiSNP Team

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Linux / Windows
  • Perl
  • matlab

:: DOWNLOAD

 QuantiSNP

:: MORE INFORMATION

Reference:

Nucleic Acids Res. 2007;35(6):2013-25. Epub 2007 Mar 6.
QuantiSNP: an Objective Bayes Hidden-Markov Model to detect and accurately map copy number variation using SNP genotyping data.
Colella S, Yau C, Taylor JM, Mirza G, Butler H, Clouston P, Bassett AS, Seller A, Holmes CC, Ragoussis J.

FRED 1.0 – Framework for T-cell Epitope Detection

FRED 1.0

:: DESCRIPTION

FRED is a framework for T-cell epitope detection that offers consistent, easy, and simultaneous access to well established prediction methods for MHC binding and antigen processing. FRED can handle polymorphic proteins and offers analysis tools to combine, benchmark, or compare different methods. It is implemented in Python in a modular way and can easily be extended by user defined methods.

DEVELOPER

the Kohlbacher lab

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Linux/ Windows with cygwin / MacOsX
  • Python

:: DOWNLOAD

 FRED

:: MORE INFORMATION

Citation:

Feldhahn, M, Dönnes, P, Thiel, P, and Kohlbacher, O (2009).
FRED – A Framework for T-cell Epitope Detection
Bioinformatics, 25(20):2758-9.

ASP 0.3 – Accurate Splice Site Detection

ASP 0.3

:: DESCRIPTION

ASP is a program to predict accurate splice sites on genomic sequences of several organisms

::DEVELOPER

Rätsch Lab

:: SCREENSHOTS

N/A

:: REQUIREMENTS

:: DOWNLOAD

 ASP

:: MORE INFORMATION

Citation

Accurate splice site prediction using support vector machines.
Sonnenburg S, Schweikert G, Philips P, Behr J, Rätsch G.
BMC Bioinformatics. 2007;8 Suppl 10:S7.

 

SADMAMA 20110410 – Motif Scanning and Detection of Significant Variation

SADMAMA 20110410

:: DESCRIPTION

SADMAMA (Significance Assessment of the Difference in MAtrix MAtches / SM) was originally designed to address the question of whether one set of sequences has more and/or better binding sites of a particular transcription factor than the other. The binding sites are modeled as matches to a, possibly gapped, position weight matrix (PWM) which is presumed to be known.

:: DEVELOPER

Uri Keich

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Linux / MacOsX / Windows
  • C Compiler

:: DOWNLOAD

 SADMAMA

:: MORE INFORMATION

Citation:

Uri Keich et al.
Computational detection of significant variation in binding affinity across two sets of sequences with application to the analysis of replication origins in yeast
BMC Bioinformatics 2008, 9:372 doi:10.1186/1471-2105-9-372

 

 

OMWSA – Detection of DNA repeats using moving window Spectral Analysis

OMWSA

:: DESCRIPTION

OMWSA (optimized moving window spectral analysis) is a new method and a visualization tool for detecting DNA repeats in a 2D plane of location and frequency by using optimized moving window spectral analysis.

::DEVELOPER

 Hong Yan , Signal Processing Lab at City University of Hong Kong

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Linux/Windows

:: DOWNLOAD

 OMWSA

:: MORE INFORMATION

Citation:

Liping Du, Hongxia Zhou and Hong Yan
OMWSA: detection of DNA repeats using moving window spectral analysis
Bioinformatics (2007) 23 (5): 631-633.

SearchRepeats – Detection of Exact Repeats by a Compression Algorithm

SearchRepeats

:: DESCRIPTION

SearchRepeats searches for exact non overlapping repeats in nucleotidic (DNA) sequences and outputs these repeats in a text report.

::DEVELOPER

Eric Rivals

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Sun Solaris

:: DOWNLOAD

 SearchRepeats

:: MORE INFORMATION

Citation

Fast Discerning Repeats in DNA Sequences with a Compression Algorithm
Rivals, M. Dauchet, J-P. Delahaye, O. Delgrange
Extended abstract in the 8th Workshop on Genome and Informatics (GIW97)
Tokyo, 12-13 Dec 1997

MEDUSA – Motif Element Detection Using Sequence Agglomeration

MEDUSA

:: DESCRIPTION

MEDUSA (Motif Element Detection Using Sequence Agglomeration) is an integrative method for learning motif models of transcription factor binding sites by incorporating promoter sequence and gene expression data. We use a modern large-margin machine learning approach, based on boosting, to enable feature selection from the high-dimensional search space of candidate binding sequences while avoiding overfitting.

::DEVELOPER

Leslie Lab

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Linux/Windows /MacOsX
  • Matlab

:: DOWNLOAD

 MEDUSA

:: MORE INFORMATION

Citation

Learning regulatory programs that accurately predict differential expression with MEDUSA.
Kundaje A, Lianoglou S, Li X, Quigley D, Arias M, Wiggins CH, Zhang L, Leslie C.
Ann N Y Acad Sci. 2007 Dec;1115:178-202. Epub 2007 Oct 12.

GPCRHMM – GPCR detection method

GPCRHMM

:: DESCRIPTION

GPCRHMM predicts G protein-coupled receptors from amino acid sequence.

::DEVELOPER

Käll Lab

:: SCREENSHOTS

N/A

:: REQUIREMENTS

:: DOWNLOAD

 GPCRHMM

:: MORE INFORMATION

Citation

Markus Wistrand*, Lukas Käll* and Erik L.L. Sonnhammer.
A general model of G protein-coupled receptor sequences and its application to detect remote homologs.
Protein Science, 15 (3):509-21, Mars 2006.

sequenceLDhot – Hotspot Detection

sequenceLDhot

:: DESCRIPTION

sequenceLDhot is further R code for implementing a penalised likelihood approach for detecting hotspots using the output of sequenceLDsr

::DEVELOPER

Prof Paul Fearnhead

:: SCREENSHOTS

N/A

:: REQUIREMENTS

:: DOWNLOAD

 sequenceLDhot

:: MORE INFORMATION

Citation

Paul Fearnhead, and Nick G.C. Smith
A novel method with improved power to detect recombination hotspots from polymorphism data reveals multiple hotspots in human genes
American Journal of Human Genetics, 77 781-794..