MEDock – Web Server for Efficient Prediction of Ligand Binding sites

MEDock

:: DESCRIPTION

MEDock (Maximum-Entropy based Docking) is a maximum-entropy based docking web server for efficient prediction of ligand binding sites

::DEVELOPER

Molecular Biomedical Informatics

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Web Borowser

:: DOWNLOAD

  NO

:: MORE INFORMATION

Citation

MEDock: a web server for efficient prediction of ligand binding sites based on a novel optimization algorithm.
Chang DT, Oyang YJ, Lin JH.
Nucleic Acids Res. 2005 Jul 1;33(Web Server issue):W233-8.

FTProd – Binding Site Comparison across Multiple Structures

FTProd

:: DESCRIPTION

This is FTProd, a plugin for VMD designed to characterize and identify cross-structural ‘hot spots’ in proteins. The program FTMAP identifies these druggable hot spots by docking a series of small molecular probes onto the protein surfaces. FTProd combines these output structures, clusters them, and displays them visually for easy comparison.

::DEVELOPER

The Amaro lab

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Linux / MacOsX / WIndows
  • VMD

:: DOWNLOAD

FTProd

:: MORE INFORMATION

Citation

Bioinformatics. 2013 Feb 1;29(3):393-4. doi: 10.1093/bioinformatics/bts689. Epub 2012 Nov 29.
Multistructural hot spot characterization with FTProd.
Votapka L, Amaro RE.

PRNA – Prediction of protein-RNA binding sites

PRNA

:: DESCRIPTION

 PRNA is a novel classificationsoftware to identify the RNA binding sites in proteins by combining a new interacting feature (interaction propensity) with other sequence- and structure-based features

::DEVELOPER

APORC

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Windows

:: DOWNLOAD

  PRNA

:: MORE INFORMATION

Citation

Liu ZP, Wu LY, Wang Y, Zhang XS, and Chen L.
Prediction of protein-RNA binding sites by a random forest method with combined features.
Bioinformatics 26(13):1616-1622.

hyfi – software suite for Binding Site Search

hyfi

:: DESCRIPTION

HyFi identifies primer and microarray probe binding sites in genomic DNA.

::DEVELOPER

Noble Research Lab

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Linux / Windows /MacOsX
  • C Compiler

:: DOWNLOAD

 hyfi

:: MORE INFORMATION

Citation

Tobias Mann and William Stafford Noble
Efficient identification of DNA hybridization partners in a sequence database
Bioinformatics (2006) 22 (14): e350-e358.

Cubic 2.0.4 / JCubic 1.1 – Protein Binding Site Prediction

Cubic 2.0.4 / JCubic 1.1

:: DESCRIPTION

Cubic is a tool to be used for protein binding site prediction.

JCUBIC is a Java-based GUI for CUBIC program which can be used for transcription factor binding site prediction.

::DEVELOPER

the Computational Systems Biology Laboratory at the University of Georgia 

:: SCREENSHOTS

:: REQUIREMENTS

  • Linux/Windows/MacOsX
  • Java

:: DOWNLOAD

 Cubic / JCubic

:: MORE INFORMATION

Citation

Victor Olman, Jizhu Lu, PhuongAn Dam, Zhengchang Su, Ying Xu.
CUBIC: Search for Binding Sites.
CSB 2004: 666-667