Tango 2.3.1 – Prediction of B-sheet Aggregation in unfolded Polypeptide Chains

Tango 2.3.1

:: DESCRIPTION

Tango is a computer algorithm for prediction of aggregating regions in unfolded polypeptide chains.The model used by the TANGO algorithm is designed to predict cross-beta aggregation in peptides and denatured proteins and consists of a phase-space encompassing the random coil and 4 possible structural states: beta-turn, alpha-helix, beta-sheet aggregation and alpha-helical aggregation.

::DEVELOPER

Serrano Group

:: REQUIREMENTS

  • Linux/ Windows

:: DOWNLOAD

 Tango

:: MORE INFORMATION

Citation

Prediction of sequence-dependent and mutational effects on the aggregation of peptides and proteins.
Fernandez-Escamilla AM, Rousseau F, Schymkowitz J, Serrano L.
Nat Biotechnol. 2004 Oct;22(10):1302-6