HitWalker2 1.0

:: DESCRIPTION

HitWalker prioritizes patient variants relative to their weighted proximity to functional assay results in a protein-protein interaction network. It is highly extensible, allowing incorporation of diverse data types to refine prioritization.

HitWalker2 is highly flexible and can utilize many data types and prioritization methods based upon available data and desired questions, allowing it to be utilized in a diverse range of studies such as cancer, infectious disease and psychiatric disorders.

::DEVELOPER

McWeeney Research Group

:: SCREENSHOTS

N/A

::REQUIREMENTS

Linux/ WIndows/MacOsX
R Package

:: DOWNLOAD

HitWalker2

:: MORE INFORMATION

Citation

HitWalker2: Visual analytics for precision medicine and beyond.
Bottomly D, McWeeney SK, Wilmot B.
Bioinformatics. 2015 Dec 26. pii: btv739

Bioinformatics. 2013 Feb 15;29(4):509-10. doi: 10.1093/bioinformatics/btt003. Epub 2013 Jan 9.
HitWalker: variant prioritization for personalized functional cancer genomics.
Bottomly D, Wilmot B, Tyner JW, Eide CA, Loriaux MM, Druker BJ, McWeeney SK.

eXtasy 0.1

:: DESCRIPTION

eXtasy is a pipeline for ranking nonsynonymous single nucleotide variants given a specific phenotype. It takes into account the putative deleteriousness of the variant, haploinsufficiency predictions of the underlying gene and the similarity of the given gene to known genes in the given phenotype.

::DEVELOPER

:: SCREENSHOTS

N/A

:: REQUIREMENTS

Linux

Ruby

R package

Tabix

BEDTool

:: DOWNLOAD

:: MORE INFORMATION

Citation

Nat Methods. 2013 Nov;10(11):1083-4. doi: 10.1038/nmeth.2656. Epub 2013 Sep 29.
eXtasy: variant prioritization by genomic data fusion.
Sifrim A, Popovic D, Tranchevent LC, Ardeshirdavani A, Sakai R, Konings P, Vermeesch JR, Aerts J, De Moor B, Moreau Y.

Tag: Variant Prioritization

HitWalker2 1.0 – Variant Prioritization for Personalized Functional Cancer Genomics

HitWalker2 1.0

eXtasy 0.1 – Variant Prioritization by Genomic data Fusion

eXtasy 0.1