DotcodeR 1.0.1 – Alignment-free comparative Genomic Screen for structured RNAs

DotcodeR 1.0.1

:: DESCRIPTION

DotcodeR is a fast and efficient method for detecting structurally similar RNAs in genomic sequences by comparing their corresponding coarse-grained secondary structure dot plots at string level.

::DEVELOPER

Yuki Kato

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Linux

:: DOWNLOAD

DotcodeR

:: MORE INFORMATION

Citation

Kato Y, Gorodkin J, Havgaard JH.
Alignment-free comparative genomic screen for structured RNAs using coarse-grained secondary structure dot plots.
BMC Genomics. 2017 Dec 2;18(1):935. doi: 10.1186/s12864-017-4309-y. PMID: 29197323; PMCID: PMC5712110.

RNAsoup 1.0a – Structural Clustering Pipeline for Structured RNAs

RNAsoup 1.0a

:: DESCRIPTION

RNAsoup  (Spot grOUPs in RNA cluster-tree) is a post-processing tool of a structural clustering pipeline for structured RNAs (e.g. RNAclust). It requires as input a binary cluster-tree, the minimum free energy (MFE) of the consensus secondary structure for each internal node, and a FASTA file of the input sequences. It detects the optimal partition (i.e. finding the optimal number of clusters/groups) into distinct subtrees where each subtree contains structurally related RNA sequences. RNAsoup is based on a decision rule which evaluates the squared error from the minimum free energies of the single sequences to the minimum free energy of the consensus secondary structure.

::DEVELOPER

Kristin Reiche

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Linux

:: DOWNLOAD

 RNAsoup

:: MORE INFORMATION

RNAstrand 2.0.0 – Predict Reading Direction of Structured RNAs in Multiple Sequence Alignments

RNAstrand 2.0.0

:: DESCRIPTION

RNAstrand predicts the reading direction of a structured RNA gene from a multiple sequence alignment and its reverse complement. It is meant as a post processing tool for RNA prediction tools which in general do not reliable annotate the reading direction of the structured RNA candidate.

RNAstrand Online Version

::DEVELOPER

Bioinformatics Leipzig

:: SCREENSHOTS

N/A

:: REQUIREMENTS

:: DOWNLOAD

 RNAstrand

:: MORE INFORMATION

Citation

RNAstrand: Reading direction of structured RNAs in multiple sequence alignments
Kristin Reiche, Peter F. Stadler,
Algorithms for Molecular Biology, 2:6, 2007.