SIMLA 3.3
:: DESCRIPTION
SIMLA (SIMulation of pedigree data for Linkage and Association studies) is a SIMulation program that generates data sets of families for use in Linkage and Association studies. It allows the user flexibility in specifying marker and disease placement, locus heterogeneity, disequilibrium between markers and between markers and disease loci. Output is in the form of a LINKAGE pedigree file and is easily utilized, either directly or with minimal reformatting, as input for various genetic analysis packages.
::DEVELOPER
Duke Molecular Physiology Institute
:: SCREENSHOTS
:: REQUIREMENTS
- Linux / MacOsX / Windows
- Java
:: DOWNLOAD
:: MORE INFORMATION
Citation
Schmidt MA, Hauser ER, Martin ER, Schmidt S.
Extension of the SIMLA package for gener ating pedigrees with complex inheritance patterns: Environmental covariates, gene-gene and gene-environment interaction.
Stat Appl Genet Mol Biol 4(1): article 15, 2005.