IDRBind – Protein Interface Predictor for Binding Sites of intrinsically disordered protein regions

IDRBind

:: DESCRIPTION

IDRBind is a protein interface predictor for binding sites of intrinsically disordered protein regions (IDRs), ranging from peptide motifs (i.e., short linear motifs) to molecular recognition features (MoRFs). Differentiating IDRBind from other interface predictors is its emphasis on binding sites of MoRFs, which are long interaction mediating elements within IDRs.

::DEVELOPER

Gsponer Lab

:: SCREENSHOTS

N/a

:: REQUIREMENTS

Web browser

:: DOWNLOAD

:: MORE INFORMATION

Citation

Wong ETC, Gsponer J.
Predicting Protein-Protein Interfaces that Bind Intrinsically Disordered Protein Regions.
J Mol Biol. 2019 Aug 9;431(17):3157-3178. doi: 10.1016/j.jmb.2019.06.010. Epub 2019 Jun 15. PMID: 31207240.

HotPoint – Hot Spot Prediction Server for Protein Interfaces

HotPoint

:: DESCRIPTION

HotPoint is a web server which predicts hot spots in protein interfaces using an empirical model.

::DEVELOPER

the COSBI (Computational Systems Biology) group

:: SCREENSHOTS

N/A

:: REQUIREMENTS

Web browser

:: DOWNLOAD

:: MORE INFORMATION

Citation

HotPoint: hot spot prediction server for protein interfaces.
Tuncbag N, Keskin O, Gursoy A.
Nucleic Acids Res. 2010 Jul;38(Web Server issue):W402-6. doi: 10.1093/nar/gkq323.

PredUs 1.2.0 – Prediction of Protein Interfaces Using Structural Alignment

PredUs 1.2.0

:: DESCRIPTION

PredUs is a flexible, interactive, template-based webserver to predict protein-protein interface of a given monomeric query protein using its close and remote structural neighbors.

::DEVELOPER

Barry Honig’s group

:: SCREENSHOTS

N/A

:: REQUIREMENTS

Web Browser

:: DOWNLOAD

:: MORE INFORMATION

Citation

PredUs: a web server for predicting protein interfaces using structural neighbors.
Zhang QC, Deng L, Fisher M, Guan J, Honig B, Petrey D.
Nucleic Acids Res. 2011 Jul;39(Web Server issue):W283-7. doi: 10.1093/nar/gkr311.

RPAIAnalyst – Exploiting Properties of Residue Pairs to Analyze Protein Interfaces

RPAIAnalyst

:: DESCRIPTION

RPAIAnalyst is a web server for exploiting properties of residue pairs to analyze protein interfaces.

::DEVELOPER

Rong Liu’s Lab of Protein Bioinformatics at Huazhong Agriculture University!

:: SCREENSHOTS

n/a

:: REQUIREMENTS

Web Browser

:: DOWNLOAD

:: MORE INFORMATION

Citation:

Protein Sci, 27 (9), 1723-1735 Sep 2018
Integrating Co-Evolutionary Signals and Other Properties of Residue Pairs to Distinguish Biological Interfaces From Crystal Contacts
Jian Hu , Hui-Fang Liu , Jun Sun , Jia Wang , Rong Liu