dcGOR 1.0.6 – Analysing Ontologies and Protein Domain Annotations

dcGOR 1.0.6

:: DESCRIPTION

dcGOR is an open-source R package for analysing domain-centric ontologies and annotations  (dcGO and others)

::DEVELOPER

Dr. Hai Fang

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Linux / Windows/ MacOsX
  • R

:: DOWNLOAD

 dcGOR

:: MORE INFORMATION

Citation:

PLoS Comput Biol. 2014 Oct 30;10(10):e1003929. doi: 10.1371/journal.pcbi.1003929. eCollection 2014.
dcGOR: an R package for analysing ontologies and protein domain annotations.
Fang H

T-RMSD – Allows fine-grained Structural Clustering of a given group of related Protein Domains

T-RMSD

:: DESCRIPTION

T-RMSD web server (tree-based on root-mean-square deviation) is a service allowing the online computation of structure-based protein classification.

::DEVELOPER

Notredame’s Lab

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Web browser

:: DOWNLOAD

 NO

:: MORE INFORMATION

Citation:

T-RMSD: a web server for automated fine-grained protein structural classification.
Magis C, Di Tommaso P, Notredame C.
Nucleic Acids Res. 2013 Jul;41(Web Server issue):W358-62. doi: 10.1093/nar/gkt383.

PhenoFam – Gene Set Enrichment Analysis in the Protein Domain Context

PhenoFam

:: DESCRIPTION

PhenoFam performs gene set enrichment analysis by employing structural and functional information on families of protein domains as annotation terms. The tool is designed to analyse complete sets of results from quantitative high-throughput studies (gene expression microarrays, functional RNAi screens, etc.) without prior pre-filtering or hits-selection steps.

::DEVELOPER

Frank Buchholz , Max Planck Institute of Molecular Cell Biology and Genetics.

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Web Browser

:: DOWNLOAD

 PhenoFam

:: MORE INFORMATION

Citation

BMC Bioinformatics. 2010 May 17;11:254. doi: 10.1186/1471-2105-11-254.
PhenoFam – gene set enrichment analysis through protein structural information.
Paszkowski-Rogacz M, Slabicki M, Pisabarro MT, Buchholz F.

Domain Fishing 1.0 – Look for Recognizable Protein Domains

Domain Fishing 1.0

:: DESCRIPTION

Domain Fishing looks for recognizable protein domains in your amino acid sequence. It tries to find good sequence matches from your sequence to every protein domain defined in PFAM , a very comprehensive database that increasingly covers the protein sequence landscape.

::DEVELOPER

Biomolecular Modelling Laboratory, Cancer Research UK London Research Institute

:: SCREENSHOTS

N/A

::REQUIREMENTS

  • Web Browser

:: DOWNLOAD

  NO

:: MORE INFORMATION

Citation

Contreras-Moreira,B. and Bates,P.A. (2002).
Domain Fishing: a first step in protein comparative modelling.
Bioinformatics 18: 1141-1142.

DOMpro 1.0 – Protein Domain Prediction

DOMpro 1.0

:: DESCRIPTION

DOMpro predicts domain locations using a 1D-RNN. DOMpro takes an input the sequence profile, predicted secondary structure, and predicted relative solvent accessiblity. The output of the 1D-RNN is a classification for each residue as being in a domain boundary region or not. The domains are then infered from this output.

::DEVELOPER

Institute for Genomics and Bioinformatics

:: SCREENSHOTS

N/A

:: REQUIREMENTS

:: DOWNLOAD

 DOMpro

:: MORE INFORMATION

Citation:

J. Cheng, M. Sweredoski, & P. Baldi.
DOMpro: Protein Domain Prediction Using Profiles, Secondary Structure, Relative Solvent Accessibility, and Recursive Neural Networks.
Knowledge Discovery and Data Mining, vol. 13, no. 1, pp. 1-20, (2006)