GRIL 1.0.0 – Genome Inversion and Rearrangement Locator

GRIL 1.0.0

:: DESCRIPTION

GRIL is a tool that can be used to identify the location of rearrangements and inversions in the backbone of a set of DNA sequences. GRIL works by identifying exactly matching regions present in all sequences under consideration and organizing them into groups of collinear regions. GRIL removes small regions of collinearity that appear unlikely to be true sequence rearrangements based on user-specified criteria such as the length of the collinear region and the percent sequence identity of the collinear region. The size of sequences that GRIL can be applied to is dependent on the amount of available memory.

::DEVELOPER

Genome Evolution Laboratory

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Linux/ Windows

:: DOWNLOAD

 GRIL

:: MORE INFORMATION

Citation:

Aaron E. Darling, Bob Mau, Frederick R. Blattner and Nicole T. Perna
GRIL: genome rearrangement and inversion locator
Bioinformatics (2004) 20 (1): 122-124.

invertFREGENE – Simulate Sequence Level data with Inversions

invertFREGENE

:: DESCRIPTION

invertFREGENE is a software for simulating sequence level data with inversions

::DEVELOPER

Dr Lachlan J Coin

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Linux / Windows/ MacOsX
  • C Compiler

:: DOWNLOAD

 invertFREGENE

:: MORE INFORMATION

Citation

Paul F. O’Reilly, Lachlan J. M. Coin and Clive J. Hoggart
invertFREGENE: software for simulating inversions in population genetic data
Bioinformatics (2010) 26 (6): 838-840.

TakeABreak 1.1.2 – Detect Inversion Breakpoints directly from raw NGS reads

TakeABreak 1.1.2

:: DESCRIPTION

TakeABreak is a tool that can detect inversion breakpoints directly from raw NGS reads, without the need of any reference genome and without de novo assembling the genomes. Its implementation has a very limited memory impact allowing its usage on common desktop computers and acceptable runtime.

::DEVELOPER

colib’read project team

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  •  Linux
  • C++ Compiler

:: DOWNLOAD

 TakeABreak

:: MORE INFORMATION

Citation

Claire Lemaitre, Liviu Ciortuz and Pierre Peterlongo,
Mapping-free and assembly-free discovery of inversion breakpoints from raw NGS reads
Proceedings of AlCoB 2014, in Algorithms for Computational Biology, LNCS vol. 8542, pp. 119–130.