RNF / RNFtools 0.3.1.3 – general Framework to Evaluate NGS Read Mappers

RNF / RNFtools  0.3.1.3

:: DESCRIPTION

RNF (Read Naming Format) is a generic format for assigning names to simulated Next-Generation Sequencing (NGS) reads.

RNFtools is an associated software package for RNF

::DEVELOPER

Boeva lab

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Linux
  • Python

:: DOWNLOAD

 RNFtools

:: MORE INFORMATION

Citation

RNF: a general framework to evaluate NGS read mappers.
B?inda K, Boeva V, Kucherov G.
Bioinformatics. 2015 Sep 9. pii: btv524.

NGS-Motif-Power – Significance and Power of Pattern Occurrences in NGS reads

NGS-Motif-Power

:: DESCRIPTION

NGS-Motif-Power is intended to calculate the p-value for pattern occurrences and the power of detecting enriched patterns in NGS reads.

::DEVELOPER

Fengzhu Sun

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Windows / Linux / MacOsX
  • Matlab

:: DOWNLOAD

  NGS-Motif-Power

:: MORE INFORMATION

Citation

Zhiyuan Zhai, Gesine Reinert, Kai Song, Michael S. Waterman, Yihui Luan, and Fengzhu Sun (2012)
Normal and Compound Poisson Approximations for Pattern Occurrences in NGS Reads.
Journal of Computational Biology.
In press.

Wombac 2.1 – Bacterial core Genome SNPs for Phylogenomic Trees from NGS Reads and/or draft genomes

Wombac 2.1

:: DESCRIPTION

Wombac rapidly finds core genome SNPs from samples and produces an alignment of those SNPs which can be used to build a phylogenomic tree.

::DEVELOPER

Torsten Seemann

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Linux
  • Perl
  • bwa mem
  • samtools

:: DOWNLOAD

 Wombac

:: MORE INFORMATION

TakeABreak 1.1.2 – Detect Inversion Breakpoints directly from raw NGS reads

TakeABreak 1.1.2

:: DESCRIPTION

TakeABreak is a tool that can detect inversion breakpoints directly from raw NGS reads, without the need of any reference genome and without de novo assembling the genomes. Its implementation has a very limited memory impact allowing its usage on common desktop computers and acceptable runtime.

::DEVELOPER

colib’read project team

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  •  Linux
  • C++ Compiler

:: DOWNLOAD

 TakeABreak

:: MORE INFORMATION

Citation

Claire Lemaitre, Liviu Ciortuz and Pierre Peterlongo,
Mapping-free and assembly-free discovery of inversion breakpoints from raw NGS reads
Proceedings of AlCoB 2014, in Algorithms for Computational Biology, LNCS vol. 8542, pp. 119–130.

NextGenMap 0.5.5 – Map NGS Reads against a Reference Genome

NextGenMap 0.5.5

:: DESCRIPTION

NextGenMap/NGM (Next Generation Mapper)is a computer program to map NGS reads against a reference genome using CPUs or GPUs.

::DEVELOPER

 the Center of Integrative Bioinformatics Vienna (CIBIV) headed by Arndt von Haeseler.

:: SCREENSHOTS

N/A

:: REQUIREMENTS

:: DOWNLOAD

 NextGenMap

:: MORE INFORMATION

Citation

Bioinformatics. 2013 Nov 1;29(21):2790-1. doi: 10.1093/bioinformatics/btt468.
NextGenMap: fast and accurate read mapping in highly polymorphic genomes.
Sedlazeck FJ, Rescheneder P, von Haeseler A.