ImmuCellAI / ImmuCellAI-mouse
:: DESCRIPTION
ImmuCellAI is a tool to estimate the abundance of 24 immune cells from gene expression dataset including RNA-Seq and microarray data, in which the 24 immune cells are comprised of 18 T-cell subtypes and 6 other immune cells: B cell, NK cell, Monocyte cell, Macrophage cell, Neutrophil cell and DC cell.
ImmuCellAI-mouse is the mouse version of ImmuCellAI. ImmuCellAI-mouse is a tool to estimate the abundance of 36 immune cells based on gene expression profile from RNA-Seq or microarray data. To ensure the prediction accuracy, we adopted a hierarchical strategy to classify the 36 cell types into three layers, which were presented as inclusion relation among different circles in the right figure.
::DEVELOPER
An-Yuan Guo’s Bioinformatics Laboratory
:: SCREENSHOTS
N/A
::REQUIREMENTS
- Web Browser
:: DOWNLOAD
NO
:: MORE INFORMATION
Citation
Miao YR, Xia M, Luo M, Luo T, Yang M, Guo AY.
ImmuCellAI-mouse: a tool for comprehensive prediction of mouse immune cell abundance and immune microenvironment depiction.
Bioinformatics. 2021 Oct 12:btab711. doi: 10.1093/bioinformatics/btab711. Epub ahead of print. PMID: 34636837.
Miao YR, Zhang Q, Lei Q, Luo M, Xie GY, Wang H, Guo AY.
ImmuCellAI: A Unique Method for Comprehensive T-Cell Subsets Abundance Prediction and its Application in Cancer Immunotherapy.
Adv Sci (Weinh). 2020 Feb 11;7(7):1902880. doi: 10.1002/advs.201902880. PMID: 32274301; PMCID: PMC7141005.