HIPPO 1.0/ AEML 1.0 – Estimate Population Haplotype Frequencies from Pooled SNP data

HIPPO 1.0/ AEML 1.0

:: DESCRIPTION

Hippo (Haplotype estimation under incomplete prior information using pooled observations) is a program for estimating haplotype distribution from pooled DNA data and is able to utilize prior information about the haplotypes that are known to be present in the population.

AEML is a program for estimating haplotype distribution from pooled DNA data and is able to utilize prior information about the haplotypes that are known to be present in the population.

::DEVELOPER

Matti Pirinen

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Linux
  • GCC

:: DOWNLOAD

  HIPPO  – AEML Source Code

:: MORE INFORMATION

Citation

Matti Pirinen
Estimating population haplotype frequencies from pooled SNP data using incomplete database information
Bioinformatics (2009) 25 (24): 3296-3302

LAPD – Estimate Maximum Likelihood Allele and two-locus Haplotype Frequencies

LAPD

:: DESCRIPTION

LAPD (Linkage Analysis Using Pedigree Data) allows to estimate maximum likelihood allele and two-locus haplotype frequencies, using an Expectation-Maximization algorithm, taking into account family relationships of the individuals.

::DEVELOPER

Computational and Molecular Population Genetics Lab, University of Bern

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Windows

:: DOWNLOAD

 LAPD

:: MORE INFORMATION

Citation

Excoffier, L. and Slatkin, M. (1998)
Incorporating genotypes of relatives into a test of linkage disequilibrium,
Am. J. Hum. Genet. 162:171-180.