Tag: FRET

FRETsg 1.0 – Structure Building from Multiple FRET Distances

FRETsg 1.0

:: DESCRIPTION

FRETsg is a tool for a fast qualitative analysis of multiple FRET (fluorescence resonance energy transfer) experiments. FRET experiments principally yield the distances between fluorescent dyes, which are commonly used for labelling proteins, DNA, RNA, etc. If multiple FRET experiments are done, it is possible to build a 3D model of the labelled positions. FRETsg finds all positions which obey the measured FRET distances and writes the model to a PDB-type file, which can be easily overlayed with other PDB structures.

::DEVELOPER

Gunnar Schröder and Helmut Grubmüller

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Windows / MacOsX /  Linux

:: DOWNLOAD

 FRETsg

:: MORE INFORMATION

Citation

Schroeder, G., & Grubmueller, H. (2004).
FRETsg: Biomolecular structure model building from multiple FRET experiments.
Computer Physics Communications, 158(3), 150-157.

FretTrace 1.0 – Maximum Likelihood Trajectories from Single-molecule FRET Experiments

FretTrace 1.0

:: DESCRIPTION

FretTrace is the implementation of a maximum likelihood based theory. Single molecule Fluorescence Resonance Energy Transfer (FRET) experiments are a powerful and versatile tool for studying conformational motions of single biomolecules at a millisecond time scale. Typically, the small number of recorded photons limits the achieved time resolution.

::DEVELOPER

Gunnar Schröder and Helmut Grubmüller

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Windows /  Linux

:: DOWNLOAD

  FretTrace

:: MORE INFORMATION

Citation

G. F. Schroder and H. Grubmuller,
Maximum likelihood trajectories from single molecule fluorescence resonance energy transfer experiments
J. Chem. Phys. 119: 9920-9924 (2003)