CytoTRACE beta – Cellular (Cyto) Trajectory Reconstruction Analysis using gene Counts and Expression

CytoTRACE beta

:: DESCRIPTION

CytoTRACE is a computational method to predict the differentiation states of cells from single-cell RNA-sequencing data, without prior knowledge of developmental orderings

::DEVELOPER

Newman Lab

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Windows/Linux
  • R

:: DOWNLOAD

CytoTRACE

:: MORE INFORMATION

Citation

Science, 367 (6476), 405-411 2020 Jan 24
Single-cell Transcriptional Diversity Is a Hallmark of Developmental Potential
Gunsagar S Gulati et al.

MS2distance – Minimum Length MS2 Folding Trajectories

MS2distance

:: DESCRIPTION

MS2distance is an algorithms to compute the shortest MS2 folding trajectory between any two given RNA secondary structures.

::DEVELOPER

Clote Lab 

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Linux /  Mac OsX / Windows
  • Python

:: DOWNLOAD

MS2distance 

:: MORE INFORMATION

FretTrace 1.0 – Maximum Likelihood Trajectories from Single-molecule FRET Experiments

FretTrace 1.0

:: DESCRIPTION

FretTrace is the implementation of a maximum likelihood based theory. Single molecule Fluorescence Resonance Energy Transfer (FRET) experiments are a powerful and versatile tool for studying conformational motions of single biomolecules at a millisecond time scale. Typically, the small number of recorded photons limits the achieved time resolution.

::DEVELOPER

Gunnar Schröder and Helmut Grubmüller

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Windows /  Linux

:: DOWNLOAD

  FretTrace

:: MORE INFORMATION

Citation

G. F. Schroder and H. Grubmuller,
Maximum likelihood trajectories from single molecule fluorescence resonance energy transfer experiments
J. Chem. Phys. 119: 9920-9924 (2003)

Kinwalker – Algorithm for Prediction of RNA Folding Trajectories

Kinwalker

:: DESCRIPTION

The  Kinwalker  algorithm performs cotranscriptional folding of RNAs, starting at a user a specified structure (default: open chain) and ending at the minimum free energy structure. Folding events are performed between transcription of additional bases and are regulated by barrier heights between the source and target structure.

::DEVELOPER

Bioinformatics Leipzig

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Linux

:: DOWNLOAD

  Kinwalker

:: MORE INFORMATION

Citation

J Mol Biol. 2008 May 23;379(1):160-73. Epub 2008 Mar 6.
Folding kinetics of large RNAs.
Geis M, Flamm C, Wolfinger MT, Tanzer A, Hofacker IL, Middendorf M, Mandl C, Stadler PF, Thurner C.