CSim 20000614 – Simulation program for Somatic Cancer Evolution

CSim 20000614

:: DESCRIPTION

 CSim simulates the evolution of a cancer starting with one cancer cell which divides and acquires mutations through the process of unequal sister chromatid exchange. The simulation starts with one cell with one chromosome pair containing 16 genes each, four essential genes (E1 to E4), four neutral genes (N1 to N4), four oncogenes (O1 to O4) and four tumor suppressor genes (T1 to T4). The order of these genes on the chromosomes can be varied as well as the frequency of mutations, the maximum length of genes involved in USCE and the number of cell divisions.  The simulation only considers the end result of reciprocal USCE where one chromatid loses and the sister chromatid gains a contiguous stretch of genetic material.

::DEVELOPER

The Independent Institute of Systems Sciences ,Aachen

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Linux

:: DOWNLOAD

 CSim

:: MORE INFORMATION

Aipotu 1.3.2 – Simulation Linking Genetics, Biochemistry, Molecular Biology & Evolution

Aipotu 1.3.2

:: DESCRIPTION

Aipotu creates a utopia that simulates the genetics, biochemistry, molecular biology, and evolution of organisms in a biologically reasonable and pedagogically relevant way.

::DEVELOPER

Brian White

:: SCREENSHOTS

:: REQUIREMENTS

  • Windows / Linux / MacOSX
  • Java

:: DOWNLOAD

Aipotu

:: MORE INFORMATION

EMOGEE 20070704 – Estimator for MOdels of Gene Expression Evolution

EMOGEE 20070704

:: DESCRIPTION

EMOGEE (Estimator for MOdels of Gene Expression Evolution) implements neutral models for evolution of gene expression to analyze or simulate microarray data.

::DEVELOPER

 the Center of Integrative Bioinformatics Vienna (CIBIV) headed by Arndt von Haeseler.

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Linux

:: DOWNLOAD

 EMOGEE

:: MORE INFORMATION

Citation:

M. Rosskopf (2007)
Development and Applications of Neutral Models for Evolution of Gene Expression,
Inaugural-Dissertation zur Erlangung des Doktorgrades der Mathematisch-Naturwissenschaftlichen Fakultät der Heinrich-Heine-Universität Düsseldorf

Darwin Rocks 1.0.3 – Evolution of Music

Darwin Rocks 1.0.3

:: DESCRIPTION

Darwin Rocks let your favourite ringtone develop by evolution! In this game music develops from the musical primordial soup onwards. Due to random mutations each song sounds a bit different and each tune has offspring that sounds various. You decide which musical creature you like and thus you increase its chance of reproduction. The continuous process of listening and rating has a big impact on the direction of development. It will lead you to some very surprising results. This all happens although each single change is just accidental. This is the power of selection.

::DEVELOPER

Darwin Rocks Team

:: SCREENSHOTS

:: REQUIREMENTS

  • Windows / MacOsX / Linux
  • Java

:: DOWNLOAD

Darwin Rocks

:: MORE INFORMATION

Contevol 1.01 – Continuous Character Evolution Teaching Program

Contevol 1.01

:: DESCRIPTION

Contevol is a simulation program designed for my class in Evolutionary Genetics. It allows the user to simulate the evolution of a quantitative character that is controlled by 5 loci, where there is a fitness function designed by the user. The user gets to see the distribution of the values of the quantitative character in a population, generation after generation. The genotypes that make up this distribution (or at any rate a representative sample of them) are displayed in the same histogram.

::DEVELOPER

Joseph Felsenstein

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Windows / MacOsX / Linux

:: DOWNLOAD

Contevol

:: MORE INFORMATION

© Copyright 2000, 2009 by the University of Washington. Permission is granted to copy this document provided that no fee is charged for it and that this copyright notice is not removed.

Ameliorator 1.0 – Calculate Amelioration Times for DNA Sequence Evolution

Ameliorator 1.0

:: DESCRIPTION

Ameliorator is a freeware program that calculates forward and backwards amelioration times for DNA sequence evolution.

::DEVELOPER

Lawrence’s Lab

:: SCREENSHOTS

:: REQUIREMENTS

  • Windows

:: DOWNLOAD

Ameliorator

:: MORE INFORMATION

Biogenesis 0.8 – Simulate Evolution of Unicellular Organisms

Biogenesis 0.8

:: DESCRIPTION

Biogenesis simulates in a visual fashion the processes involved in the evolution of unicellular organisms at nature. It tries to be a didactic approximation to the ideas of mutation or evolution and can be enjoyed also as an entertainment. It’s intended to serve as a support to show students some basic biological facts.

::DEVELOPER

Joan Queralt Molina (joanq.biogenesis at gmail.com)

:: SCREENSHOTS

:: REQUIREMENTS

  • Windows / Linux / Mac OsX
  • Java

:: DOWNLOAD

Biogenesis

:: MORE INFORMATION

This program is free software and it is distributed under the terms of the GNU General Public License. Take a look to copyright and gpl.txt files for further information.

Evolver – Whole-genome Sequence Evolution Simulator

Evolver

:: DESCRIPTION

Evolver is a collection of programs designed to simulate the evolution of the nucleotide sequence of a whole genome. Evolver simulates the evolution of a representative genome of a species over periods long compared with its generation time.

::DEVELOPER

Robert Edgar , George Asimenos, Serafim Batzoglou and Arend Sidow.

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Linux

:: DOWNLOAD

Evolver

:: MORE INFORMATION

N/A