DICER – Differential Correlation in Expression for meta-module Recovery

DICER

:: DESCRIPTION

DICER is a tool for advanced analysis of differential co-expression (DC) case-control gene expression data.

::DEVELOPER

Ron Shamir’s lab

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Windows/Linux/ MacOsX
  • Java 

:: DOWNLOAD

 DICER

:: MORE INFORMATION

Citation

PLoS Comput Biol. 2013;9(3):e1002955. doi: 10.1371/journal.pcbi.1002955. Epub 2013 Mar 7.
Dissection of regulatory networks that are altered in disease via differential co-expression.
Amar D1, Safer H, Shamir R.

PHDcleav – Prediction of Human Dicer Cleavage

PHDcleav

:: DESCRIPTION

PHDcleav is a webserver to predict Dicer cleavage sites in pre-miRNA. Dicer, an RNase III enzyme, plays vital role in RNA interference pathway, processes both pre-miRNAs (precursor microRNAs) and double-stranded (ds) RNAs to generate effector molecules. Thus it is very important to know true Dicer processing sites in the pre-miRNA molecules to understand the RNA interference pathway.

::DEVELOPER

PHDcleav team 

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Web Browser

:: DOWNLOAD

 NO

:: MORE INFORMATION

Citation

BMC Bioinformatics. 2013;14 Suppl 14:S9. doi: 10.1186/1471-2105-14-S14-S9. Epub 2013 Oct 9.
PHDcleav: a SVM based method for predicting human Dicer cleavage sites using sequence and secondary structure of miRNA precursors.
Ahmed F, Kaundal R, Raghava GP.