Tag: Deleterious

MutPred2 – Predicting whether an Amino Acid Substitution in a protein is Deleterious or Neutral

MutPred2

:: DESCRIPTION

MutPred is a web application tool developed to classify an amino acid substitution as disease-associated or neutral in human. In addition, it predicts molecular cause of disease.

::DEVELOPER

MutPred team

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Linux

:: DOWNLOAD

MutPred2

:: MORE INFORMATION

Citation

Bioinformatics. 2009 Nov 1;25(21):2744-50. doi: 10.1093/bioinformatics/btp528. Epub 2009 Sep 3.
Automated inference of molecular mechanisms of disease from amino acid substitutions.
Li B, Krishnan VG, Mort ME, Xin F, Kamati KK, Cooper DN, Mooney SD, Radivojac P.

PhD-SNP 2.0.6 – Predictor of human Deleterious Single Nucleotide Polymorphisms

PhD-SNP 2.0.6

:: DESCRIPTION

PhD-SNP supports Vector Machine based method to discriminate between neutral or disease-related single point protein mutations.

::DEVELOPER

the Structural Bioinformatics Unit

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Linux / Mac / Windows
  • Python

:: DOWNLOAD

 PhD-SNP

:: MORE INFORMATION

Citation

Bioinformatics. 2006 Nov 15;22(22):2729-34. Epub 2006 Aug 7.
Predicting the insurgence of human genetic diseases associated to single point protein mutations with support vector machines and evolutionary information.
Capriotti E, Calabrese R, Casadio R.