LineUp – Statistical Detection of Chromosomal Homology

LineUp

:: DESCRIPTION

LineUp is a software for statistical detection of chromosomal homology with application to plant comparative genomics.

::DEVELOPER

Institute for Genomics and Bioinformatics 

:: REQUIREMENTS

  • Linux / Windows / MacOsX
  • Perl

:: DOWNLOAD

  LineUp

:: MORE INFORMATION

Citation:

Steve Hampson, Aoife McLysaght, Brandon S. Gaut, and Pierre F. Baldi.
LineUp: Statistical Detection of Chromosomal Homology With Application to Plant Comparative Genomics
Genome Research (2003) 13: 999-1010

CloseUp – Detect Chromosomal Homology Using Gene Density Alone

CloseUp

:: DESCRIPTION

CloseUp is a new algorithm for the statistical detection of chromosomal homology, which uses shared-gene density alone to fully exploit the observation that relaxing colinearity requirements in general is beneficial for homology detection and at the same time optimizes computation time. CloseUp has two components: the identification of candidate homologous regions followed by their statistical evaluation using Monte Carlo methods and data randomization.

::DEVELOPER

Institute for Genomics and Bioinformatics 

:: REQUIREMENTS

  • Linux / Windows / MacOsX
  • Perl

:: DOWNLOAD

  CloseUp

:: MORE INFORMATION

Citation:

S. Hampson, B.S. Gaut, and P. Baldi.
CloseUp: Statistical Detection of Chromosomal Homology Using Shared-Gene Density Alone.
Bioinformatics , 21, 8, 1339-1348, (2005).