CloseUp
:: DESCRIPTION
CloseUp is a new algorithm for the statistical detection of chromosomal homology, which uses shared-gene density alone to fully exploit the observation that relaxing colinearity requirements in general is beneficial for homology detection and at the same time optimizes computation time. CloseUp has two components: the identification of candidate homologous regions followed by their statistical evaluation using Monte Carlo methods and data randomization.
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::DEVELOPER
Institute for Genomics and Bioinformatics
:: REQUIREMENTS
- Linux / Windows / MacOsX
- Perl
:: DOWNLOAD
:: MORE INFORMATION
Citation:
S. Hampson, B.S. Gaut, and P. Baldi.
CloseUp: Statistical Detection of Chromosomal Homology Using Shared-Gene Density Alone.
Bioinformatics , 21, 8, 1339-1348, (2005).