MHC – Matrix Optimization Technique for Predicting MHC binding Core

MHC

:: DESCRIPTION

MHC server was used Matrix Optimization Technique to predict MHC binding core.

::DEVELOPER

G P S Raghava
,
:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Web Browser

:: DOWNLOAD

  NO

:: MORE INFORMATION

Citation

Singh, H. and Raghava, G. P. S. (2002)
Detection of Orientation of MHC Class II Binding Peptides Using Bioinformatics Tools
Biotech Software and Internet Report, 3:146

SVMotif 0.1 – A SVM Based Transcription Factor Binding Motif Finder

SVMotif 0.1

:: DESCRIPTION

SVMotif is a mechine learning based motif finder. It can be classified into K-mer enumeration based methods. the evaluation of each possible K-mer is done by Recursive SVM feature selection

::DEVELOPER

Mark KonYue Fan

:: SCREENSHOTS

n/A

:: REQUIREMENTS

  • Linux / Windows/ MacOsX
  • Java/ Matlab

:: DOWNLOAD

  SVMotif

:: MORE INFORMATION

Citation

Ensemble machine methods for DNA binding
(with Y. Fan, and C. DeLisi),
Machine Learning and Applications 7, M. Wani, et al., eds. IEEE, Washington (2008),709-716.

MetalloPred – Hierarchical Prediction of Metal Ion Binding proteins

MetalloPred

:: DESCRIPTION

MetalloPred is developed which consists of 3 level of hierarchical classification using cascade of neural networks from sequence derived features. The 1st layer of the prediction engine is for identifying a query protein as metalloprotein or not; the 2nd layer for the main functional class; and the 3rd layer for the sub-functional class.

::DEVELOPER

MetalloPred Team

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Windows / Linux /MacOsX
  • Java
  • EMBOSS 
  • Perl

:: DOWNLOAD

 MetalloPred

:: MORE INFORMATION

Citation

Pradeep K. Naik, Piyush Ranjan, Pooja Kesari and Sankalp Jain (2011).
MetalloPred: A tool for hierarchical prediction of metal ion binding proteins using cluster of neural networks and sequence derived features.
Journal of Biophysical Chemistry, 2(2): 112-123.

CooperativeDimer – Analysis of Ligand Binding to Dimers

CooperativeDimer

:: DESCRIPTION

CooperativeDimer is a software developed in Mathematica for the analysis of the affinities and any cooperativity in ligand binding to a dimer (or other molecule containing two equivalent binding sites). The approach requires data on the fractional populations of all three species (apo, singly and doubly bound) such as may be obtained from mass spectrometry or NMR data.

::DEVELOPER

Mark A. Williams

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Linux / Windows / MacOsX
  • Mathematica

:: DOWNLOAD

  CooperativeDimer

:: MORE INFORMATION

Citation

Marcus J. Edwards, Mark A. Williams, Anthony Maxwell and Adam R. McKay (2011).
Mass spectrometry reveals the antibiotic simocyclinone D8 binds DNA gyrase in “bent over” conformation: evidence for positive coperativity.
Biochemistry. 2011 May 3;50(17):3432-40. Epub 2011 Apr 5.