AlloSigMA 2 – Allosteric Signalling and Mutation Analysis

AlloSigMA 2

:: DESCRIPTION

The AlloSigMA server is a tool for estimating the allosteric free energies acting on a single residue as a result of either ligand binding, mutations, or both combined.

::DEVELOPER

Bioinformatics Institute (BII), Singapore.

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Web Browser

:: DOWNLOAD

 NO

:: MORE INFORMATION

Citation

Tan ZW, Guarnera E, Tee WV, Berezovsky IN.
AlloSigMA 2: paving the way to designing allosteric effectors and to exploring allosteric effects of mutations.
Nucleic Acids Res. 2020 Jul 2;48(W1):W116-W124. doi: 10.1093/nar/gkaa338. PMID: 32392302; PMCID: PMC7319554.

Dynamical Network Analysis – Characterizing Allosteric Signalling through Biomolecular Complexes

Dynamical Network Analysis

:: DESCRIPTION

Dynamical Network Analysis is a method of characterizing allosteric signalling through biomolecular complexes.

::DEVELOPER

The Luthey-Schulten Group – University of Illinois at Urbana-Champaign

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Windows/Linux/MacOsX

:: DOWNLOAD

  Dynamical Network Analysis

:: MORE INFORMATION

Citation

Dynamical networks in tRNA:protein complexes.
Sethi A, Eargle J, Black AA, Luthey-Schulten Z.
Proc Natl Acad Sci U S A. 2009 Apr 21;106(16):6620-5