MetaPhase
:: DESCRIPTION
MetaPhase is a software tool to perform metagenomic deconvolution. That is, it inputs a metagenome assembly – an assembly created from a mixed genomic sample, usually of many different microbial species – and it determines which contigs in that assembly belong together in the same genomes. A metagenome assembly does not contain the complete genomes of any one species in the mixed sample, but the deconvoluted assembly can contain nearly complete genomes of many individual species. MetaPhase relies on data generated by Hi-C, an established molecular technique of studying chromatin conformation.
::DEVELOPER
:: SCREENSHOTS
N/A
:: REQUIREMENTS
- Linux
- C++
:: DOWNLOAD
:: MORE INFORMATION
Citation
Burton JN, Liachko I, Dunham MJ, Shendure J.
Species-level deconvolution of metagenome assemblies with Hi-C-based contact probability maps.
G3 (Bethesda). 2014 May 22;4(7):1339-46. doi: 10.1534/g3.114.011825. PMID: 24855317; PMCID: PMC4455782.