VASCo 1.0.2 – Computation and Visualization of Annotated Protein Surface Contacts

VASCo 1.0.2


VASCo is a program pipeline including a visualization tool to calculate and visualize annotated surfaces with special emphasis on surface contact regions and protein-protein interactions. Crystal contacts and biological contacts can be calculated based on surface points. Molecular properties such as electrostatic potential or hydrophobicity can be calculated and mapped on those surface points. The molecular surfaces and properties are calculated using existing established programs, which are integrated into the package, as well as using own developed programs. The modular pipeline can easily be extended to include new properties for annotation. The output of this pipeline is most conveniently displayed in PyMOL as Compiled Graphics Objects (CGO) using a custom-made plug-in.



Genomics & Bioinformatics Graz, Graz University of Technology



  • Linux / Windows / MacOsX
  • Python
  • Mymol





Steinkellner G, Rader R, Thallinger GG, Kratky C, Gruber K.
VASCo: computation and visualization of annotated protein surface contacts
BMC Bioinformatics 2009, 10(1):32

Leave a Reply

Your email address will not be published. Required fields are marked *

This site uses Akismet to reduce spam. Learn how your comment data is processed.