Vacceed 1.1 – in silico Vaccine Discovery pipeline for Eukaryotic Pathogens

Vacceed 1.1

:: DESCRIPTION

Vacceed is a highly configurable and scalable framework designed to automate the process of high-throughput in silico vaccine candidate discovery for eukaryotic pathogens.

::DEVELOPER

Vacceed team

:: SCREENSHOTS

N/A

:: REQUIREMENTS

Linux

:: DOWNLOAD

Vacceed

:: MORE INFORMATION

Citation

Bioinformatics. 2014 Apr 29. pii: btu300. [Epub ahead of print]
Vacceed: a high-throughput in silico vaccine candidate discovery pipeline for eukaryotic pathogens based on reverse vaccinology.
Goodswen SJ, Kennedy PJ, Ellis JT.

EPISOFT – Epitope Vaccine Optimization Server

EPISOFT

:: DESCRIPTION

EPISOFT predicts epitope HLA I binding profiles and computes population protection (PPC). It also identifies minimal sets of epitopes that reach a target PPC for 5 distinct user-selected ethnic groups.

::DEVELOPER

Immunomedicine Group

:: SCREENSHOTS

N/A

:: REQUIREMENTS

Web browser

:: DOWNLOAD

:: MORE INFORMATION

Citation:

Towards the Knowledge-based Design of Universal Influenza Epitope Ensemble Vaccines.
Sheikh QM, Gatherer D, Reche PA, Flower DR.
Bioinformatics. 2016 Jul 10. pii: btw399.

pVACtools 2.0.1 – Tools for Personalized Cancer Vaccine Design

pVACtools 2.0.1

:: DESCRIPTION

pVACtools is a computational toolkit for aiding design of personalized cancer vaccines.

::DEVELOPER

The Griffith Lab

:: SCREENSHOTS

N/A

:: REQUIREMENTS

Linux/MacOsX
Python

:: DOWNLOAD

pVACtools

:: MORE INFORMATION

Citation

Hundal, Kiwala et al. 2020.
pVACtools: A Computational Toolkit to Identify and Visualize Cancer Neoantigens.
Cancer Immunology Research. 8(3):409-420.

VaccineDA – Designing Vaccine Adjuvants based on immunomodulatory DNA

VaccineDA

:: DESCRIPTION

VaccineDA is a webserver in order to assist the experimentalists in designing better IMODN based adjuvants using sequence information of the oligonucleotides. The models used in prediction have been developed on experimentally validated IMODNs using different Datasets.

::DEVELOPER

VaccineDA team

:: SCREENSHOTS

N/A

:: REQUIREMENTS

Web Browser

:: DOWNLOAD

:: MORE INFORMATION

Citation

VaccineDA: Prediction, design and genome-wide screening of oligodeoxynucleotide-based vaccine adjuvants.
Nagpal G, Gupta S, Chaudhary K, Dhanda SK, Prakash S, Raghava GP.
Sci Rep. 2015 Jul 27;5:12478. doi: 10.1038/srep12478.

MtbVeb – Designing Vaccine for Mycobacterium Tuberculosis

MtbVeb

:: DESCRIPTION

MtbVeb is a web-based platform developed for designing vaccines against existing and emerging strains of mycobacterium tuberculosis. This includes drug resistant and extreme drug resistant M.Tb strains. It also allow users to design vaccines against M.tb using all three appraoches (strain, antigen and epitope based vaccines).

::DEVELOPER

MtbVeb team

:: SCREENSHOTS

N/A

:: REQUIREMENTS

Web Browser

:: DOWNLOAD

:: MORE INFORMATION

Citation

A Web-Based Platform for Designing Vaccines against Existing and Emerging Strains of Mycobacterium tuberculosis.
Dhanda SK, Vir P, Singla D, Gupta S, Kumar S, Raghava GP.
PLoS One. 2016 Apr 20;11(4):e0153771. doi: 10.1371/journal.pone.0153771.

Cancertope – Designing genome-based Personalized Immunotherapy or Vaccine against Cancer

Cancertope

:: DESCRIPTION

Cancertope is a platform which developed for designing genome-based immunotherapy or vaccine against a cancer cell.

::DEVELOPER

Cancertope team

:: SCREENSHOTS

N/A

:: REQUIREMENTS

Web Browser

:: DOWNLOAD

:: MORE INFORMATION

Citation

A Platform for Designing Genome-Based Personalized Immunotherapy or Vaccine against Cancer.
Gupta S, Chaudhary K, Dhanda SK, Kumar R, Kumar S, Sehgal M, Nagpal G, Raghava GP.
PLoS One. 2016 Nov 10;11(11):e0166372. doi: 10.1371/journal.pone.0166372.