GenoClone 0.1 – subClone inference and studying Tumor Heterogenity

GenoClone 0.1

:: DESCRIPTION

GenoClone aims to provide useful tool to infer the tumor subclones and study tumor heterogeneity.

::DEVELOPER

Au Lab

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Linux

:: DOWNLOAD

GenoClone

:: MORE INFORMATION

Citation

Zou M, Jin R, Au KF.
Revealing tumor heterogeneity of breast cancer by utilizing the linkage between somatic and germline mutations.
Brief Bioinform. 2019 Nov 27;20(6):2306-2315. doi: 10.1093/bib/bby084. PMID: 30239581; PMCID: PMC6954402.

TreeClone v1 – Reconstruction of Tumor Subclone Phylogeny Based on Mutation Pairs using Next Generation Sequencing Data

TreeClone v1

:: DESCRIPTION

TreeClone is a latent feature allocation model to reconstruct tumor subclones subject to phylogenetic evolution that mimics tumor evolution.

::DEVELOPER

Yuan Ji Lab

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Linux / Windows / MacOsX
  • R package

:: DOWNLOAD

TreeClone

:: MORE INFORMATION

Citation

[Submitted on 10 Mar 2017 (v1), last revised 25 Oct 2017 (this version, v2)]
TreeClone: Reconstruction of Tumor Subclone Phylogeny Based on Mutation Pairs using Next Generation Sequencing Data
Tianjian Zhou, Subhajit Sengupta, Peter Mueller, Yuan Ji