SNPSpD / SNPSpDlite
SNPSpD is a method of correcting for non-independence of SNPs in LD with each other
SNPSpDlite takes the same input at SNPSpD, but ONLY outputs the LD correlation matrix, Meff and MeffLi estimates and GOLD input (i.e., does not perform time-consuming varimax/promax rotations) thus allowing users to obtain Meff/MeffLi values for large numbers (1000s) of SNPs.
the Statistical and Genomic Epidemiology Laboratory (SGEL)
- Web Browser
:: MORE INFORMATION
Am J Hum Genet. 2004 Apr;74(4):765-9. Epub 2004 Mar 2.
A simple correction for multiple testing for single-nucleotide polymorphisms in linkage disequilibrium with each other.