CARE – Computational Analysis of REsistance

CARE

:: DESCRIPTION

CARE is a software developed to enable large-scale inference of response biomarkers and drug combinations for targeted therapies using compound screen data.

::DEVELOPER

X. Shirley Liu Lab

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Linux

:: DOWNLOAD

CARE

:: MORE INFORMATION

Citation

Cell Syst. 2018 Mar 28;6(3):343-354.e5. doi: 10.1016/j.cels.2018.01.009.
Genome-Scale Signatures of Gene Interaction from Compound Screens Predict Clinical Efficacy of Targeted Cancer Therapies.
Jiang P, Lee W, Li X, Johnson C, Liu JS, Brown M5 Aster JC, Liu XS.

HerceptinR – Database of Herceptin Resistance

HerceptinR

:: DESCRIPTION

HerceptinR is a database of assays performed to test sensitivity or resistance of Herceptin Antibodies towards breast cancer cell lines. This database provides comprehensive information about experimental data perform to understanding factors behind herceptin resistance aas well as assays peformed for improving Herceptin sensitivity with the help of supplementary drugs.

::DEVELOPER

HerceptinR team

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Web Browser

:: DOWNLOAD

 NO

:: MORE INFORMATION

Citation

Herceptin resistance database for understanding mechanism of resistance in breast cancer patients.
Ahmad S, Gupta S, Kumar R, Varshney GC, Raghava GP.
Sci Rep. 2014 Mar 27;4:4483. doi: 10.1038/srep04483.