CGAP-Align 0.1.1 – Time Efficient Read Alignment tool built on the top of BWA

CGAP-Align 0.1.1

:: DESCRIPTION

CGAP-align is a new program that achieves a performance improvement over BWA without sacrificing recall or precision.

::DEVELOPER

CGAP-Align team

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Linux

:: DOWNLOAD

  CGAP-Align

:: MORE INFORMATION

Citation

PLoS One. 2013 Apr 11;8(4):e61033. doi: 10.1371/journal.pone.0061033. Print 2013.
CGAP-align: a high performance DNA short read alignment tool.
Chen Y1, Hong J, Cui W, Zaneveld J, Wang W, Gibbs R, Xiao Y, Chen R.

SeqAlto 0.5-r123 – Fast and Accurate Read Alignment for Resequencing

SeqAlto 0.5-r123

:: DESCRIPTION

 SeqAlto is an aligner specifically designed for Illumina reads of length greater or equal to about 100-bp. It takes advantage of this longer read length to provide fast alignment rates and accurate placement of polymorphic reads. Paired-end reads are recommended for even greater accuracy. When aligning 100-bp paired-end reads SeqAlto is on average about 2-4x faster than BWA while being more sensitive and much faster for longer reads.

::DEVELOPER

Wong Lab

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • MacOsX/  Linux

:: DOWNLOAD

 SeqAlto

:: MORE INFORMATION

Citation

John C. Mu, Hui Jiang, Amirhossein Kiani, Marghoob Mohiyuddin, Narges Bani Asadi and Wing H. Wong,
Fast and Accurate Read Alignment for Resequencing,
Bioinformatics (2012) 28 (18): 2366-2373.

RC454 1.2 – Read Alignment and Error Correction tool for Cleaning 454 Reads of Process Errors

RC454 1.2

:: DESCRIPTION

RC454 (ReadClean454) is a program that takes a set of 454 read and quality files as well as a consensus assembly for those reads and corrects for known 454 error modes such as homopolymer indels and carry forward/incomplete extension (CAFIE).It will also correct for any indel that breaks the reading frame, unless it occurs in more than 25% of the reads.

::DEVELOPER

Computational R&D, The Broad Institute, Cambridge, MA

:: SCREENSHOTS

N/A

:: REQUIREMENTS

  • Linux

:: DOWNLOAD

 RC454

:: MORE INFORMATION