MORPHEUS
:: DESCRIPTION
MORPHEUS is a tool to identify and rebuild residues in predicted models with a large error. The error in predicted models is estimated using the average pairwise geometric distance per residue computed among selected lowest energy models. This error distribution among residues is employed to guide the rebuilding process that focuses on more error-prone residues of the coarse-grain models.
::DEVELOPER
Structural Bioinformatics Team
:: SCREENSHOTS
N/A
:: REQUIREMENTS
- Linux
:: DOWNLOAD
:: MORE INFORMATION
Citation
Acta Crystallogr D Biol Crystallogr. 2012 Nov;68(Pt 11):1522-34. doi: 10.1107/S0907444912037961. Epub 2012 Oct 18.
Error-estimation-guided rebuilding of de novo models increases the success rate of ab initio phasing.
Shrestha R1, Simoncini D, Zhang KY.